Literature DB >> 19082145

Catalytic asymmetric synthesis of the alkaloid (+)-myrtine.

Maria Gabriella Pizzuti1, Adriaan J Minnaard, Ben L Feringa.   

Abstract

A new protocol for the asymmetric synthesis of trans-2,6-disubstituted-4-piperidones has been developed using a catalytic enantioselective conjugate addition reaction in combination with a diastereoselective lithiation-substitution sequence; an efficient synthesis of (+)-myrtine has been achieved via this route.

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Year:  2008        PMID： 19082145     DOI： 10.1039/b807575a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  4 in total

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Journal:  Angew Chem Int Ed Engl       Date:  2019-07-30       Impact factor: 15.336

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Authors:  Vartika Srivastava; Mohmmad Younus Wani; Abdullah Saad Al-Bogami; Aijaz Ahmad
Journal:  J Adv Res       Date:  2020-11-10       Impact factor: 10.479

4.  Enantioselective Catalytic Dearomative Addition of Grignard Reagents to 4-Methoxypyridinium Ions.

Authors:  Yafei Guo; Marta Castiñeira Reis; Johanan Kootstra; Syuzanna R Harutyunyan
Journal:  ACS Catal       Date:  2021-06-28       Impact factor: 13.084
  4 in total

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