Literature DB >> 19081366

Putting a KAP on transcription and stress.

Mark D Alter1, Rene Hen.   

Abstract

Chromatin regulation plays an important role in brain development and the generation of phenotypic diversity. In this issue of Neuron, Jakobsson et al. find that disruption in neurons of KAP1, a key component of transcriptional repressor complexes in the brain, results in increased anxiety-like behavior and sensitivity to stress.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 19081366     DOI： 10.1016/j.neuron.2008.12.002

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  4 in total

1.  MMSET stimulates myeloma cell growth through microRNA-mediated modulation of c-MYC.

Authors:  D-J Min; T Ezponda; M K Kim; C M Will; E Martinez-Garcia; R Popovic; V Basrur; K S Elenitoba-Johnson; J D Licht
Journal:  Leukemia       Date:  2012-09-13       Impact factor: 11.528

2.  TRIM28 is required by the mouse KRAB domain protein ZFP568 to control convergent extension and morphogenesis of extra-embryonic tissues.

Authors:  Maho Shibata; Kristin E Blauvelt; Karel F Liem; María J García-García
Journal:  Development       Date:  2011-12       Impact factor: 6.868

3.  A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1.

Authors:  Vikram Narayan; Petr Halada; Lenka Hernychová; Yuh Ping Chong; Jitka Žáková; Ted R Hupp; Borivoj Vojtesek; Kathryn L Ball
Journal:  J Biol Chem       Date:  2011-01-18       Impact factor: 5.157

Review 4.  Bromodomains as therapeutic targets.

Authors:  Susanne Muller; Panagis Filippakopoulos; Stefan Knapp
Journal:  Expert Rev Mol Med       Date:  2011-09-13       Impact factor: 5.600
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.