| Literature DB >> 19081259 |
Sarah J H Hickford1, John W Blunt, Murray H G Munro.
Abstract
The isolation is reported of four new variants of the halichondrin B skeleton, very minor potently bioactive components from the Poecilosclerid sponge Lissodendoryx sp. These compounds were isolated in microgram quantities only from a collection of 1tonne of sponge. The structural elucidations relied heavily on the use of capillary NMR spectroscopy and the application of an HSQC-DEPT overlay technique.Entities:
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Year: 2008 PMID： 19081259 DOI： 10.1016/j.bmc.2008.10.093
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641