Literature DB >> 19080772

[Malignant multiple neoplasms in head and neck squamous cell carcinoma].

Celia López Mollá1, Enrique Estellés Ferriol, Marina Carrasco Llatas, Teresa Seijas Rosales, María Morales Suárez-Varela, José Dalmau Galofre.   

Abstract

INTRODUCTION: The incidence of multiple malignant neoplasms in the upper aerodigestive tract is high and ranges from 7% to 20%. We make a retrospective study to evaluate the incidence of multiple malignant neoplasms in head and neck squamous cell carcinomas, their main characteristics and survival. MATERIAL AND
METHOD: We studied 103 multiple malignant neoplasms from an oncological database of 1330 patients with head and neck squamous cell carcinomas. We use the SPSS v15 for analysis of the results.
RESULTS: The incidence of multiple malignant neoplasms in our series is 7.73 %. Tumours of the hypopharynx are the primary tumours most often associated with multiple malignant neoplasms (21.34 %), followed by tumours of the oropharynx (15.38 %). Lung tumours are the multiple malignant neoplasms most often associated (29.03 %). The 5-year global survival is 33 % from diagnosis of the second primary tumour, 78.02 % of which are metachronous with an average of 40 months between the diagnosis of the primary tumour and the presentation of the second tumour.
CONCLUSIONS: Multiple malignant neoplasms are very frequent in the head and neck area which shows the importance of thorough regular check-ups of these patients as the presence of multiple malignant neoplasms considerably worsens the prognosis.

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Mesh:

Year:  2008        PMID: 19080772

Source DB:  PubMed          Journal:  Acta Otorrinolaringol Esp        ISSN: 0001-6519


  2 in total

1.  Prognostic impact of second primary tumors in head and neck cancer.

Authors:  Marta S Patrucco; Marina V Aramendi
Journal:  Eur Arch Otorhinolaryngol       Date:  2015-06-29       Impact factor: 2.503

2.  Multidisciplinary treatment based on surgery leading to long-term survival of a patient with multiple asynchronous rare primary malignant neoplasms: A case report and literature review.

Authors:  Hong-Lin Gu; Shi-Xing Zeng; Yun-Bing Chang; Zhen Lin; Qiu-Jian Zheng; Xiao-Qing Zheng; Zhen-Wei Peng; Shi-Qiang Zhan
Journal:  Oncol Lett       Date:  2014-12-29       Impact factor: 2.967

  2 in total

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