Literature DB >> 19079769

Object-oriented Bayesian networks for paternity cases with allelic dependencies.

Amanda B Hepler1, Bruce S Weir.   

Abstract

This study extends the current use of Bayesian networks by incorporating the effects of allelic dependencies in paternity calculations. The use of object-oriented networks greatly simplify the process of building and interpreting forensic identification models, allowing researchers to solve new, more complex problems. We explore two paternity examples: the most common scenario where DNA evidence is available from the alleged father, the mother and the child; a more complex casewhere DNA is not available from the alleged father, but is available from the alleged father's brother. Object-oriented networks are built, using HUGIN, for each example which incorporate the effects of allelic dependence caused by evolutionary relatedness.

Entities:  

Keywords:  Avuncular index; DNA evidence; Evidence interpretation; Paternity index; Probabilistic expert systems

Mesh:

Year:  2008        PMID: 19079769      PMCID: PMC2600569          DOI: 10.1016/j.fsigen.2007.12.003

Source DB:  PubMed          Journal:  Forensic Sci Int Genet        ISSN: 1872-4973            Impact factor:   4.882


  16 in total

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8.  Population genetics of STR loci in Caucasians.

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  5 in total

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3.  DNA identification by pedigree likelihood ratio accommodating population substructure and mutations.

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Journal:  Investig Genet       Date:  2010-10-04

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5.  Current developments in forensic interpretation of mixed DNA samples (Review).

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