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Literature DB >> 19079220

Innate immune recognition of the indigenous microbial flora.

Abstract

Our studies have focused on understanding the mechanisms of interactions between the indigenous intestinal flora and the mammalian host in both physiological and nonphysiological conditions. In particular, we have focused on the function of innate microbial pattern recognition by Toll-like receptors in the context of tissue injury and repair, spontaneous colitis, and postnatal development.

Entities: Disease Species

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Year: 2008 PMID： 19079220 DOI： 10.1038/mi.2008.49

Source DB: PubMed Journal: Mucosal Immunol ISSN： 1933-0219 Impact factor: 7.313

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Cited

38 in total

1. Epithelial cell proliferation in the developing zebrafish intestine is regulated by the Wnt pathway and microbial signaling via Myd88.

Authors: Sarah E Cheesman; James T Neal; Erika Mittge; Barbara M Seredick; Karen Guillemin
Journal: Proc Natl Acad Sci U S A Date: 2010-10-04 Impact factor: 11.205

Review 2. Role of the gut microbiota in defining human health.

Authors: Kei E Fujimura; Nicole A Slusher; Michael D Cabana; Susan V Lynch
Journal: Expert Rev Anti Infect Ther Date: 2010-04 Impact factor: 5.091

3. Down-regulation of single immunoglobulin interleukin-1R-related molecule (SIGIRR)/TIR8 expression in intestinal epithelial cells during inflammation.

Authors: C Kadota; S Ishihara; M M Aziz; M A Rumi; N Oshima; Y Mishima; I Moriyama; T Yuki; Y Amano; Y Kinoshita
Journal: Clin Exp Immunol Date: 2010-11 Impact factor: 4.330

Innate immune recognition of the indigenous microbial flora.

1. Epithelial cell proliferation in the developing zebrafish intestine is regulated by the Wnt pathway and microbial signaling via Myd88.

Review 2. Role of the gut microbiota in defining human health.

3. Down-regulation of single immunoglobulin interleukin-1R-related molecule (SIGIRR)/TIR8 expression in intestinal epithelial cells during inflammation.

Review 4. Gastrointestinal malignancy and the microbiome.

5. Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells.

Review 6. Overview of cytokines and nitric oxide involvement in immuno-pathogenesis of inflammatory bowel diseases.

7. Intestinal Host-Microbe Interactions under Physiological and Pathological Conditions.

Review 8. The infant gut bacterial microbiota and risk of pediatric asthma and allergic diseases.

Review 9. The role of the intestinal microbiota in enteric infection.

10. Lactobacillus casei abundance is associated with profound shifts in the infant gut microbiome.