Literature DB >> 19079076

From rapid in vitro screening to rapid in vivo screening in the drug discovery process.

F Ivy Carroll1, Richard A Houghten.   

Abstract

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Year:  2009        PMID： 19079076     DOI： 10.1038/npp.2008.160

Source DB:  PubMed          Journal:  Neuropsychopharmacology        ISSN： 0893-133X            Impact factor:   7.853


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  4 in total

Review 1.  Shifting from the single to the multitarget paradigm in drug discovery.

Authors:  José L Medina-Franco; Marc A Giulianotti; Gregory S Welmaker; Richard A Houghten
Journal:  Drug Discov Today       Date:  2013-01-20       Impact factor: 7.851

2.  Identification of two novel, potent, low-liability antinociceptive compounds from the direct in vivo screening of a large mixture-based combinatorial library.

Authors:  Kate J Reilley; Marc Giulianotti; Colette T Dooley; Adel Nefzi; Jay P McLaughlin; Richard A Houghten
Journal:  AAPS J       Date:  2010-04-27       Impact factor: 4.009

3.  The Effect of Fluphenazine and Thioridazine on Toxoplasma gondii In Vivo.

Authors:  Mehrzad Saraei; Yosef Ghaderi; Tahereh Mosavi; Mojtaba Shahnazi; Marjan Nassiri-Asl; Hassan Jahanihashemi
Journal:  Iran J Parasitol       Date:  2016 Apr-Jun       Impact factor: 1.012

4.  Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734,821 Pyrrolidine Bis-piperazines.

Authors:  Richard A Houghten; Michelle L Ganno; Jay P McLaughlin; Colette T Dooley; Shainnel O Eans; Radleigh G Santos; Travis LaVoi; Adel Nefzi; Greg Welmaker; Marc A Giulianotti; Lawrence Toll
Journal:  ACS Comb Sci       Date:  2016-01-05       Impact factor: 3.784
  4 in total

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