Dipen Shah1. 1. Unit of Electrophysiology, Cardiology Service, Hopital Cantonal Universitaire de Genéve, Geneva, Switzerland. dipen.shah@hcuge.ch
Abstract
PURPOSE OF REVIEW: The present popularity of catheter ablation for atrial fibrillation has generated interest in the pathophysiology of arrhythmias originating from the left atrium. An improved understanding of ECG manifestations of reentrant left atrial arrhythmias has obvious clinical implications. An ideal goal would be to achieve diagnostic precision similar to the 'sawtooth' ECG morphology of typical atrial flutter. RECENT FINDINGS: Recent studies have shown that nonreentrant arrhythmias originating from the left atrium are characterized by specific ECG features of the P wave, the most consistent being a positive or a dominantly positive deflection in V1. Similarly, bystander activation of the right atrium generates a dominantly positive deflection in V1 even during left atrial reentry. Although continuous reentrant activation should generate continuous electrical activity on surface ECG, this may not be the case if part of the reentry circuit generates feeble electrical forces, for example, a thin strand of myocardium. As a result, discrete P waves separated by a 12-lead synchronous isoelectric interval may be produced. Their morphology can be used to infer the location of the exit from this slow-conducting isthmus and facilitate ablation. SUMMARY: The progressive accumulation of accurate activation mapping data of the full spectrum of left atrial reentry will certainly allow the development of clinically useful ECG algorithms.
PURPOSE OF REVIEW: The present popularity of catheter ablation for atrial fibrillation has generated interest in the pathophysiology of arrhythmias originating from the left atrium. An improved understanding of ECG manifestations of reentrant left atrial arrhythmias has obvious clinical implications. An ideal goal would be to achieve diagnostic precision similar to the 'sawtooth' ECG morphology of typical atrial flutter. RECENT FINDINGS: Recent studies have shown that nonreentrant arrhythmias originating from the left atrium are characterized by specific ECG features of the P wave, the most consistent being a positive or a dominantly positive deflection in V1. Similarly, bystander activation of the right atrium generates a dominantly positive deflection in V1 even during left atrial reentry. Although continuous reentrant activation should generate continuous electrical activity on surface ECG, this may not be the case if part of the reentry circuit generates feeble electrical forces, for example, a thin strand of myocardium. As a result, discrete P waves separated by a 12-lead synchronous isoelectric interval may be produced. Their morphology can be used to infer the location of the exit from this slow-conducting isthmus and facilitate ablation. SUMMARY: The progressive accumulation of accurate activation mapping data of the full spectrum of left atrial reentry will certainly allow the development of clinically useful ECG algorithms.
Authors: Hugh Calkins; Karl Heinz Kuck; Riccardo Cappato; Josep Brugada; A John Camm; Shih-Ann Chen; Harry J G Crijns; Ralph J Damiano; D Wyn Davies; John DiMarco; James Edgerton; Kenneth Ellenbogen; Michael D Ezekowitz; David E Haines; Michel Haissaguerre; Gerhard Hindricks; Yoshito Iesaka; Warren Jackman; Jose Jalife; Pierre Jais; Jonathan Kalman; David Keane; Young-Hoon Kim; Paulus Kirchhof; George Klein; Hans Kottkamp; Koichiro Kumagai; Bruce D Lindsay; Moussa Mansour; Francis E Marchlinski; Patrick M McCarthy; J Lluis Mont; Fred Morady; Koonlawee Nademanee; Hiroshi Nakagawa; Andrea Natale; Stanley Nattel; Douglas L Packer; Carlo Pappone; Eric Prystowsky; Antonio Raviele; Vivek Reddy; Jeremy N Ruskin; Richard J Shemin; Hsuan-Ming Tsao; David Wilber Journal: J Interv Card Electrophysiol Date: 2012-03 Impact factor: 1.900
Authors: Craig T January; L Samuel Wann; Joseph S Alpert; Hugh Calkins; Joaquin E Cigarroa; Joseph C Cleveland; Jamie B Conti; Patrick T Ellinor; Michael D Ezekowitz; Michael E Field; Katherine T Murray; Ralph L Sacco; William G Stevenson; Patrick J Tchou; Cynthia M Tracy; Clyde W Yancy Journal: Circulation Date: 2014-03-28 Impact factor: 29.690