Literature DB >> 19075768

Pharmacogenomics and personalized use of drugs.

Jing-Fang Wang1, Dong-Qing Wei, Kuo-Chen Chou.   

Abstract

As the development of the Human Genome Project (HGP), the sequencing of whole human genome has been completed, and a series of human genes have been detected, both of which result in the naissance of pharmacogenomics. Pharmacogenomics is the study of how an individual's genetic inheritance affects the body's response to drugs using the information of human genomics and bioinformatics approaches. It is not only propitious to the rational use of drugs, but also in favor for the personalized drug design.

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Year:  2008        PMID: 19075768     DOI: 10.2174/156802608786786534

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN: 1568-0266            Impact factor:   3.295


  5 in total

1.  Exploration of conformational transition in the aryl-binding site of human FXa using molecular dynamics simulations.

Authors:  Jing-Fang Wang; Pei Hao; Yi-Xue Li; Jian-Liang Dai; Xuan Li
Journal:  J Mol Model       Date:  2011-11-25       Impact factor: 1.810

2.  Predicting drug-target interaction networks based on functional groups and biological features.

Authors:  Zhisong He; Jian Zhang; Xiao-He Shi; Le-Le Hu; Xiangyin Kong; Yu-Dong Cai; Kuo-Chen Chou
Journal:  PLoS One       Date:  2010-03-11       Impact factor: 3.240

3.  Insights from modeling the 3D structure of New Delhi metallo-β-lactamse and its binding interactions with antibiotic drugs.

Authors:  Jing-Fang Wang; Kuo-Chen Chou
Journal:  PLoS One       Date:  2011-04-11       Impact factor: 3.240

4.  DrugECs: An Ensemble System with Feature Subspaces for Accurate Drug-Target Interaction Prediction.

Authors:  Jinjian Jiang; Nian Wang; Peng Chen; Jun Zhang; Bing Wang
Journal:  Biomed Res Int       Date:  2017-07-04       Impact factor: 3.411

5.  Prediction of drug-target interactions from multi-molecular network based on LINE network representation method.

Authors:  Bo-Ya Ji; Zhu-Hong You; Han-Jing Jiang; Zhen-Hao Guo; Kai Zheng
Journal:  J Transl Med       Date:  2020-09-07       Impact factor: 5.531

  5 in total

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