Literature DB >> 19074706

Methadone exposure during lactation.

Miguel Marcelo Glatstein1, Facundo Garcia-Bournissen, Yaron Finkelstein, Gideon Koren.   

Abstract

QUESTION: One of my patients is currently using methadone for maintenance of opioid dependence. She wants to breastfeed. Is breastfeeding safe for her infant? ANSWER: The exposure of infants to methadone through their mothers' breast milk is minimal. Women using methadone for treatment of opioid dependence should not be discouraged from breastfeeding. The benefits of breastfeeding largely outweigh any theoretical minimal risks.

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Year:  2008        PMID： 19074706      PMCID： PMC2602642     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN： 0008-350X            Impact factor:   3.275


  15 in total

1.  Methadone and breastfeeding: new horizons.

Authors:  Barbara L Philipp; Anne Merewood; Susan O'Brien
Journal:  Pediatrics       Date:  2003-06       Impact factor: 7.124

2.  Opiate exposure in breastfeeding newborns.

Authors:  Elissa Meites
Journal:  J Hum Lact       Date:  2007-02       Impact factor: 2.219

3.  Reducing potential for child abuse among methadone-maintained parents: results from a randomized controlled trial.

Authors:  Sharon Dawe; Paul Harnett
Journal:  J Subst Abuse Treat       Date:  2006-12-08

4.  Methadone maintenance and breastfeeding in the neonatal period.

Authors:  Anthony J W Liu; Ralph Nanan
Journal:  Pediatrics       Date:  2008-04       Impact factor: 7.124

5.  The costs of crime and the benefits of substance abuse treatment for pregnant women.

Authors:  M Daley; M Argeriou; D McCarty; J J Callahan; D S Shepard; C N Williams
Journal:  J Subst Abuse Treat       Date:  2000-12

6.  Methadone distribution and excretion into breast milk of clients in a methadone maintenance programme.

Authors:  R E Wojnar-Horton; J H Kristensen; P Yapp; K F Ilett; L J Dusci; L P Hackett
Journal:  Br J Clin Pharmacol       Date:  1997-12       Impact factor: 4.335

Review 7.  Transfer of drugs and other chemicals into human milk.

Authors: 
Journal:  Pediatrics       Date:  2001-09       Impact factor: 7.124

8.  Neonatal abstinence syndrome following abrupt cessation of breastfeeding.

Authors:  T J Malpas; B A Darlow
Journal:  N Z Med J       Date:  1999-01-22

9.  Effects of breast milk on the severity and outcome of neonatal abstinence syndrome among infants of drug-dependent mothers.

Authors:  Mohamed E Abdel-Latif; Jason Pinner; Sara Clews; Fiona Cooke; Kei Lui; Julee Oei
Journal:  Pediatrics       Date:  2006-06       Impact factor: 7.124

10.  Role of CYP2B6 in stereoselective human methadone metabolism.

Authors:  Rheem A Totah; Pamela Sheffels; Toni Roberts; Dale Whittington; Kenneth Thummel; Evan D Kharasch
Journal:  Anesthesiology       Date:  2008-03       Impact factor: 7.892
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  2 in total

1.  Maternal Substance Use and Neonatal Abstinence Syndrome: A Descriptive Study.

Authors:  Karen A McQueen; Jodie Murphy-Oikonen; Lindsay Desaulniers
Journal:  Matern Child Health J       Date:  2015-08

2.  Pain relief after cesarean section: Oral methadone vs. intramuscular pethidine.

Authors:  Azar Danesh Shahraki; Mitra Jabalameli; Somayeh Ghaedi
Journal:  J Res Med Sci       Date:  2012-02       Impact factor: 1.852
  2 in total

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