Literature DB >> 19072520

Impact of obesity on female fertility and fertility treatment.

Murizah M Zain1, Robert J Norman.   

Abstract

Obesity and overweight are common conditions that have consequences not only on general health but also to a great extent on reproductive health. There is a high prevalence of obese women in the infertile population and numerous studies have highlighted the link between obesity and infertility. Obesity contributes to anovulation and menstrual irregularities, reduced conception rate and a reduced response to fertility treatment. It also increases miscarriage and contributes to maternal and perinatal complication. Reduction of obesity, particularly abdominal obesity, is associated with improvements in reproductive functions; hence, treatment of obesity itself should be the initial aim in obese infertile women before embarking on ovulation-induction drugs or assisted reproductive techniques. While various strategies for weight reduction, including diet, exercise, pharmacological and surgical intervention exist, lifestyle modification continues to be of paramount importance.

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Year:  2008        PMID: 19072520     DOI: 10.2217/17455057.4.2.183

Source DB:  PubMed          Journal:  Womens Health (Lond)        ISSN: 1745-5057


  31 in total

1.  Hippocrates: timeless still.

Authors:  Eleni Tsiompanou; Spyros G Marketos
Journal:  J R Soc Med       Date:  2013-07       Impact factor: 5.344

2.  Progressive obesity alters ovarian folliculogenesis with impacts on pro-inflammatory and steroidogenic signaling in female mice.

Authors:  Jackson Nteeba; Shanthi Ganesan; Aileen F Keating
Journal:  Biol Reprod       Date:  2014-08-20       Impact factor: 4.285

3.  High fat diet affects reproductive functions in female diet-induced obese and dietary resistant rats.

Authors:  P Balasubramanian; L Jagannathan; Rochell E Mahaley; M Subramanian; E T Gilbreath; P S Mohankumar; S M J Mohankumar
Journal:  J Neuroendocrinol       Date:  2012-05       Impact factor: 3.627

4.  Sleeve Gastrectomy Reversed Obesity-Induced Hypogonadism in a Rat Model by Regulating Inflammatory Responses in the Hypothalamus and Testis.

Authors:  Jun Xiang; Cuidong Bian; Xiaodong Wan; Qimin Zhang; Shengsong Huang; Denglong Wu
Journal:  Obes Surg       Date:  2018-08       Impact factor: 4.129

Review 5.  The effect of obesity on sperm disorders and male infertility.

Authors:  Stefan S Du Plessis; Stephanie Cabler; Debra A McAlister; Edmund Sabanegh; Ashok Agarwal
Journal:  Nat Rev Urol       Date:  2010-02-16       Impact factor: 14.432

6.  Binge eating and menstrual dysfunction.

Authors:  Monica Algars; Lu Huang; Ann F Von Holle; Christine M Peat; Laura M Thornton; Paul Lichtenstein; Cynthia M Bulik
Journal:  J Psychosom Res       Date:  2013-11-28       Impact factor: 3.006

7.  Leptin-Induced CART (Cocaine- and Amphetamine-Regulated Transcript) Is a Novel Intraovarian Mediator of Obesity-Related Infertility in Females.

Authors:  Xiaoting Ma; Emily Hayes; Hen Prizant; Rajesh K Srivastava; Stephen R Hammes; Aritro Sen
Journal:  Endocrinology       Date:  2016-01-05       Impact factor: 4.736

8.  Role of syndecan-3 polymorphisms in obesity and female hyperandrogenism.

Authors:  Andreas N Schüring; Friederike Lutz; Frank Tüttelmann; Jörg Gromoll; Ludwig Kiesel; Martin Götte
Journal:  J Mol Med (Berl)       Date:  2009-10-07       Impact factor: 4.599

9.  Feasibility of a brief, intensive weight loss intervention to improve reproductive outcomes in obese, subfertile women: a pilot study.

Authors:  Amy Rothberg; Michael Lanham; John Randolph; Christine Fowler; Nicole Miller; Yolanda Smith
Journal:  Fertil Steril       Date:  2016-06-20       Impact factor: 7.329

Review 10.  Hormones in synergy: regulation of the pituitary gonadotropin genes.

Authors:  Varykina G Thackray; Pamela L Mellon; Djurdjica Coss
Journal:  Mol Cell Endocrinol       Date:  2009-09-10       Impact factor: 4.102

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