Literature DB >> 19072212

Copper-catalyzed 2:1 coupling reaction of arynes with alkynes.

Hiroto Yoshida1, Takami Morishita, Hiromi Nakata, Joji Ohshita.   

Abstract

A formal insertion reaction of two molar amounts of arynes into a C-H bond of terminal alkynes is efficaciously catalyzed by copper(I) chloride, giving 2-alkynylbiaryls in one step.

Entities:  

Year:  2009        PMID： 19072212     DOI： 10.1021/ol802609j

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  CuI -Mediated Bromoalkynylation and Hydroalkynylation Reactions of Unsymmetrical Benzynes: Complementary Modes of Addition.

Authors:  Xiao Xiao; Tao Wang; Feng Xu; Thomas R Hoye
Journal:  Angew Chem Int Ed Engl       Date:  2018-11-15       Impact factor: 15.336

2.  Palladium-catalyzed annulation of arynes by o-halobenzamides: synthesis of phenanthridinones.

Authors:  Chun Lu; Anton V Dubrovskiy; Richard C Larock
Journal:  J Org Chem       Date:  2012-09-26       Impact factor: 4.354

3.  Transition-metal-free alkynylation of aryl chlorides.

Authors:  Thanh Truong; Olafs Daugulis
Journal:  Org Lett       Date:  2011-07-25       Impact factor: 6.005

4.  Copper Catalysis for Synthesizing Main-Group Organometallics Containing B, Sn or Si.

Authors:  Hiroto Yoshida
Journal:  Chem Rec       Date:  2016-01-20       Impact factor: 6.771

5.  Cu(I)-Catalyzed 1,2-Alkynyl-propargylation and -benzylation of Benzyne Derivatives.

Authors:  Qile Wang; Thomas R Hoye
Journal:  Org Lett       Date:  2021-06-28       Impact factor: 6.072
  5 in total

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