Literature DB >> 1907214

Morphological transformation of microglia in vitro.

A Suzumura1, T Marunouchi, H Yamamoto.   

Abstract

Isolated microglia underwent in vitro morphological transformation to ameboid, rod-shaped and ramified forms in response to several cytokines, factors from astrocytes, or factors which affect macrophage function. These morphological transformations were reversible. Examination of the enzymatic activity, superoxide anion formation and proliferative activity of these transformed microglia indicated that the ameboid forms were activated, rod-shaped microglia were proliferating, and the ramified forms were resting microglia.

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Year:  1991        PMID: 1907214     DOI: 10.1016/0006-8993(91)91302-h

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  23 in total

1.  Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils.

Authors:  J Frackowiak; H M Wisniewski; J Wegiel; G S Merz; K Iqbal; K C Wang
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

2.  Soluble tumor necrosis factor receptor inhibits interleukin 12 production by stimulated human adult microglial cells in vitro.

Authors:  B Becher; V Dodelet; V Fedorowicz; J P Antel
Journal:  J Clin Invest       Date:  1996-10-01       Impact factor: 14.808

3.  Lipofuscin-dependent stimulation of microglial cells.

Authors:  Martin Dominik Leclaire; Gerburg Nettels-Hackert; Jeannette König; Annika Höhn; Tilman Grune; Constantin E Uhlig; Uwe Hansen; Nicole Eter; Peter Heiduschka
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2019-01-28       Impact factor: 3.117

4.  Apoptosis of primary-culture rat microglial cells induced by pathogenic Acanthamoeba spp.

Authors:  H J Shin; M S Cho; H I Kim; M Lee; S Park; S Sohn; K I Im
Journal:  Clin Diagn Lab Immunol       Date:  2000-05

5.  Cytopathic changes in rat microglial cells induced by pathogenic Acanthamoeba culbertsoni: morphology and cytokine release.

Authors:  H J Shin; M S Cho; S Y Jung; H I Kim; S Park; J H Seo; J C Yoo; K I Im
Journal:  Clin Diagn Lab Immunol       Date:  2001-07

6.  Neuronal regulation of glutamate transporter subtype expression in astrocytes.

Authors:  R A Swanson; J Liu; J W Miller; J D Rothstein; K Farrell; B A Stein; M C Longuemare
Journal:  J Neurosci       Date:  1997-02-01       Impact factor: 6.167

7.  Targeting NLRP3 signaling by a novel-designed sulfonylurea compound for inhibition of microglial inflammation.

Authors:  Changwen Zhang; Ayyiliath M Sajith; Xiaotian Xu; Jianxiong Jiang; J Phillip Bowen; Amol Kulkarni; Jiukuan Hao
Journal:  Bioorg Med Chem       Date:  2022-01-31       Impact factor: 3.641

Review 8.  Colony stimulating factors in the nervous system.

Authors:  Violeta Chitu; Fabrizio Biundo; E Richard Stanley
Journal:  Semin Immunol       Date:  2021-11-04       Impact factor: 11.130

9.  Dynamics of actin filaments in microglia during Fc receptor-mediated phagocytosis.

Authors:  E M Abd-el-Basset; S Fedoroff
Journal:  Acta Neuropathol       Date:  1994       Impact factor: 17.088

10.  Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro.

Authors:  Vibol Chhor; Tifenn Le Charpentier; Sophie Lebon; Marie-Virgine Oré; Idoia Lara Celador; Julien Josserand; Vincent Degos; Etienne Jacotot; Henrik Hagberg; Karin Sävman; Carina Mallard; Pierre Gressens; Bobbi Fleiss
Journal:  Brain Behav Immun       Date:  2013-02-27       Impact factor: 7.217

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