| Literature DB >> 19070569 |
Abstract
The Bcl-2 family protein Bax is a key effector of apoptosis. Lovell et al. (2008) now describe the reconstitution and regulation in liposomes of tBid-mediated membrane penetration and oligomerization of Bax. These and other recent studies shed new light on the control of permeabilization of the mitochondrial outer membrane during apoptosis.Entities:
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Year: 2008 PMID: 19070569 DOI: 10.1016/j.cell.2008.11.029
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582