OBJECTIVE: To evaluate the difference in trace elements between diabetic and control groups, and to explore the correlations between trace elements and serum glucose, body compositions in patients with type 2 diabetes mellitus. METHODS: 72 diabetics and 64 controls are selected randomly. The level of serum trace elements, the ratio of copper, zinc were measured and compared between the two groups. A correlation was conducted for the serum trace elements, serum glucose and body compositions and 64 controls are selected randomly. RESULTS: There was a very significant difference in some serum trace elements level between diabetic and control groups (P < 0.01). Serum zinc, selenium,chromium were significantly lower in diabetic group compared with the control group (P < 0.01), copper was significantly higher (P < 0.01). Negative correlations were showed between zinc and serum glucose, manganese and the content of protein, the content of trace elements, hip circumference. And positive correlations were showed between copper and serum glucose, copper and waist circumference. CONCLUSION: It is concluded that there is trace elements metabolism disorder in patients with type 2 diabetes mellitus. The correction for this disorder might have significant value for the treatment of diabetics and prevention of complications.
OBJECTIVE: To evaluate the difference in trace elements between diabetic and control groups, and to explore the correlations between trace elements and serum glucose, body compositions in patients with type 2 diabetes mellitus. METHODS: 72 diabetics and 64 controls are selected randomly. The level of serum trace elements, the ratio of copper, zinc were measured and compared between the two groups. A correlation was conducted for the serum trace elements, serum glucose and body compositions and 64 controls are selected randomly. RESULTS: There was a very significant difference in some serum trace elements level between diabetic and control groups (P < 0.01). Serum zinc, selenium,chromium were significantly lower in diabetic group compared with the control group (P < 0.01), copper was significantly higher (P < 0.01). Negative correlations were showed between zinc and serum glucose, manganese and the content of protein, the content of trace elements, hip circumference. And positive correlations were showed between copper and serum glucose, copper and waist circumference. CONCLUSION: It is concluded that there is trace elements metabolism disorder in patients with type 2 diabetes mellitus. The correction for this disorder might have significant value for the treatment of diabetics and prevention of complications.
Authors: M Estakhri; A Djazayery; Mr Eshraghian; R Majdzadeh; M Jalali; Z Karamizadeh; M Chamari; M Peyrovi Milani Journal: Iran J Public Health Date: 2011-12-31 Impact factor: 1.429