Literature DB >> 19069078

The standardization of race and ethnicity in biomedical science editorials and UK biobanks.

Andrew Smart1, Richard Tutton, Paul Martin, George T H Ellison, Richard Ashcroft.   

Abstract

As the search for human genetic variation has become a priority for biomedical science, debates have resurfaced about the use of race and ethnicity as scientific classifications. In this paper we consider the relationship between race, ethnicity and genetics, using insights from science and technology studies (STS) about processes of classification and standardization. We examine how leading biomedical science journals attempted to standardize the classifications of race and ethnicity, and analyse how a sample of UK genetic scientists used the concepts in their research. Our content analysis of 11 editorials and related guidelines reveals variations in the guidance on offer, and it appears that there has been a shift from defining the concepts to prescribing methodological processes for classification. In qualitative interviews with 17 scientists, the majority reported that they had adopted socio-political classification schemes from state bureaucracy (for example, the UK Census) for practical reasons, although some scientists used alternative classifications that they justified on apparently methodological grounds. The different responses evident in the editorials and interviews can be understood as reflecting the balance of flexibility and stability that motivate standardization processes. We argue that, although a genetic concept of race and ethnicity is unlikely to wholly supplant a socio-political one, the adoption of census classifications into biomedical research is an alignment of state bureaucracy and science that could have significant consequences.

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Year:  2008        PMID: 19069078     DOI: 10.1177/0306312707083759

Source DB:  PubMed          Journal:  Soc Stud Sci        ISSN: 0306-3127            Impact factor:   3.885


  11 in total

1.  Characterization of clinical study populations by race and ethnicity in biomedical literature.

Authors:  Priyanka Kanakamedala; Susanne B Haga
Journal:  Ethn Dis       Date:  2012       Impact factor: 1.847

Review 2.  Matrix metalloproteinases and tissue inhibitors of metalloproteinases in chronic kidney disease and acute kidney injury: a systematic review of the literature.

Authors:  C L Sampieri; R A Orozco-Ortega
Journal:  Hippokratia       Date:  2018 Jul-Sep       Impact factor: 0.471

Review 3.  Population description and its role in the interpretation of genetic association.

Authors:  Stephanie M Fullerton; Joon-Ho Yu; Julia Crouch; Kelly Fryer-Edwards; Wylie Burke
Journal:  Hum Genet       Date:  2010-02-16       Impact factor: 4.132

4.  Principles for research on ethnicity and health: the Leeds Consensus Statement.

Authors:  Ghazala Mir; Sarah Salway; Joe Kai; Saffron Karlsen; Raj Bhopal; George Th Ellison; Aziz Sheikh
Journal:  Eur J Public Health       Date:  2012-05-02       Impact factor: 3.367

5.  Epigenome data release: a participant-centered approach to privacy protection.

Authors:  Stephanie O M Dyke; Warren A Cheung; Yann Joly; Ole Ammerpohl; Pavlo Lutsik; Mark A Rothstein; Maxime Caron; Stephan Busche; Guillaume Bourque; Lars Rönnblom; Paul Flicek; Stephan Beck; Martin Hirst; Henk Stunnenberg; Reiner Siebert; Jörn Walter; Tomi Pastinen
Journal:  Genome Biol       Date:  2015-07-17       Impact factor: 13.583

6.  Explaining the visible and the invisible: Public knowledge of genetics, ancestry, physical appearance and race in Colombia.

Authors:  Ernesto Schwartz-Marín; Peter Wade
Journal:  Soc Stud Sci       Date:  2015-12       Impact factor: 3.885

7.  Sharing health-related data: a privacy test?

Authors:  Stephanie Om Dyke; Edward S Dove; Bartha M Knoppers
Journal:  NPJ Genom Med       Date:  2016-08-17       Impact factor: 8.617

8.  'Foreigners', 'ethnic minorities', and 'non-Western allochtoons': an analysis of the development of 'ethnicity' in health policy in the Netherlands from 1970 to 2015.

Authors:  Alana Helberg-Proctor; Agnes Meershoek; Anja Krumeich; Klasien Horstman
Journal:  BMC Public Health       Date:  2017-01-31       Impact factor: 3.295

9.  Inclusion of Indigenous Australians in biobanks: a step to reducing inequity in health care.

Authors:  Imogen Elsum; Callum McEwan; Emma E Kowal; Yvonne Cadet-James; Margaret Kelaher; Lynn Woodward
Journal:  Med J Aust       Date:  2019-06-03       Impact factor: 7.738

Review 10.  Racial categories in medicine: a failure of evidence-based practice?

Authors:  George T H Ellison; Andrew Smart; Richard Tutton; Simon M Outram; Richard Ashcroft; Paul Martin
Journal:  PLoS Med       Date:  2007-09       Impact factor: 11.069

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