BACKGROUND: Metastatic tumors of thyroid are uncommonly reported from fine needle aspiration (FNA), although well documented in autopsy series. Soft tissue sarcomas metastasizing to the thyroid are even rarer. CASE: A 30-year-old woman who was nown to have malignant fibrous histiocytoma arising in the soft tissues of the medial aspect of the ankle presented with a midline thyroid swelling, firm in consistency and moving with deglutition. FNA smears from the thyroid swelling showed discretely lying and loosely cohesive clusters of malignant cells admixed with benign thyroid follicular cells. The features were consirtent with metastases from a sarcoma. CONCLUSION: The rare occurrence of a sarcoma metastasizing to the thyroid can be easily diagnosed by FNA cytology provided the primary is manifest and/or comparison with the primary or immunocytochemistry investigation is available.
BACKGROUND:Metastatic tumors of thyroid are uncommonly reported from fine needle aspiration (FNA), although well documented in autopsy series. Soft tissue sarcomas metastasizing to the thyroid are even rarer. CASE: A 30-year-old woman who was nown to have malignant fibrous histiocytoma arising in the soft tissues of the medial aspect of the ankle presented with a midline thyroid swelling, firm in consistency and moving with deglutition. FNA smears from the thyroid swelling showed discretely lying and loosely cohesive clusters of malignant cells admixed with benign thyroid follicular cells. The features were consirtent with metastases from a sarcoma. CONCLUSION: The rare occurrence of a sarcoma metastasizing to the thyroid can be easily diagnosed by FNA cytology provided the primary is manifest and/or comparison with the primary or immunocytochemistry investigation is available.
Authors: Alexander Kreze; Andrea Zápotocká; Tomáš Urbanec; Jiří Koskuba; Mikuláš Pura; Pavel Vítek; Pavol Praženica; Eva Traboulsi Journal: Case Rep Med Date: 2012-10-24