| Literature DB >> 190678 |
R M Herndon, D L Price, L P Weiner.
Abstract
Infection of mice with the JHM strain of mouse hepatitis virus causes demyelination as a result of a cytolytic infection of oligodendroglia. In recovery, animals show remyelination, which could result either from surviving oligodendrocytes extending their territory or by generation of new oligodendroglia. Electron microscopic autoradiographic studies with 3H-labeled thymidine demonstrate that the cells associated with remyelination are newly generated oligodendroglia.Entities:
Mesh：
Substances：
Year: 1977 PMID： 190678 DOI： 10.1126/science.190678
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728