Literature DB >> 190674

Tremor caused by sympathomimetics is mediated by beta2-adrenoreceptors.

S Larsson, N Svedmyr.   

Abstract

Tremor caused by beta-adrenostimulating drugs is known to be mediated by beta-receptors in skeletal muscles. In this study it was shown that tremor caused by terbutaline could be blocked by propranolol, a drug with both beta1- and beta2-blocking properties, but not by metoprolol, a beta1-selective antagonist. It is concluded that tremor caused by sympathomimetics in man is mainly mediated by beta2-receptors.

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Year:  1977        PMID： 190674

Source DB:  PubMed          Journal:  Scand J Respir Dis        ISSN： 0036-5572


  17 in total

1.  Sympathomimetic bronchodilators: increased selectivity with lung-specific prodrugs.

Authors:  L A Svensson
Journal:  Pharm Res       Date:  1985-07       Impact factor: 4.200

2.  In vitro studies on the relative potency of bronchodilator agents.

Authors:  J H Fleisher; J L Pinnas
Journal:  Lung       Date:  1985       Impact factor: 2.584

3.  Enhancement of physiological finger tremor by intravenous isoprenaline infusions in man: evaluation of its role in the assessment of beta-adrenoceptor antagonists.

Authors:  J M Arnold; D G McDevitt
Journal:  Br J Clin Pharmacol       Date:  1984-08       Impact factor: 4.335

4.  Beta-adrenoceptor blocking drugs and partial agonist activity. Is it clinically relevant?

Authors:  D G McDevitt
Journal:  Drugs       Date:  1983-04       Impact factor: 9.546

5.  Exercise-induced hand tremor: a possible test for beta 2-adrenoceptor selectivity in man?

Authors:  B Abila; J F Wilson; R W Marshall; A Richens
Journal:  Br J Clin Pharmacol       Date:  1986-07       Impact factor: 4.335

6.  Cardiac, pulmonary and neuromuscular effects of clenbuterol and terbutaline compared with placebo.

Authors:  T L Whitsett; C V Manion; M F Wilson
Journal:  Br J Clin Pharmacol       Date:  1981-08       Impact factor: 4.335

7.  The effect of propranolol versus placebo on resident surgical performance.

Authors:  M J Elman; J Sugar; R Fiscella; T A Deutsch; J Noth; M Nyberg; K Packo; R J Anderson
Journal:  Trans Am Ophthalmol Soc       Date:  1998

8.  Central beta-adrenoceptors can modulate 5-hydroxytryptamine-induced tremor in rats.

Authors:  H Hallberg
Journal:  Br J Pharmacol       Date:  1986-02       Impact factor: 8.739

9.  The tremorolytic action of beta-adrenoceptor blockers in essential, physiological and isoprenaline-induced tremor is mediated by beta-adrenoceptors located in a deep peripheral compartment.

Authors:  B Abila; J F Wilson; R W Marshall; A Richens
Journal:  Br J Clin Pharmacol       Date:  1985-10       Impact factor: 4.335

10.  The selective beta 1-blocking agent metoprolol compared with antithyroid drug and thyroxine as preoperative treatment of patients with hyperthyroidism. Results from a prospective, randomized study.

Authors:  A Adlerberth; G Stenström; P O Hasselgren
Journal:  Ann Surg       Date:  1987-02       Impact factor: 12.969
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