Literature DB >> 19067381

In vitro effects of glycyrrhetinic acid on the growth of clinical isolates of Candida albicans.

Donatella Pellati1, Cristina Fiore, Decio Armanini, Mario Rassu, Giulio Bertoloni.   

Abstract

Compounds derived from Glycyrrhiza glabra L. root have been used widely for centuries for their numerous therapeutic properties. The present study aimed to test the in vitro activity against Candida albicans strains of the compound 18-beta glycyrrhetinic acid (18-beta GA), derived from the root of Glycyrrhiza species. This antimicrobial activity was assessed using the National Committee for Clinical Laboratory Standards (NCCLS) method on C. albicans strains that were isolated from patients with recurrent vulvovaginal candidiasis (RVVC). The in vitro growth of the C. albicans strains was markedly reduced, in a pH-dependent manner, by relatively low doses (6.2 microg/mL) of 18-beta GA. The results demonstrate that 18-beta GA is a promising biological alternative for the topical treatment of recurrent vulvovaginal candidiasis (RVVC). (c) 2008 John Wiley & Sons, Ltd.

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Year:  2009        PMID： 19067381     DOI： 10.1002/ptr.2693

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  6 in total

1.  Isolation and characterization of three fungi with the potential of transforming glycyrrhizin.

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Journal:  World J Microbiol Biotechnol       Date:  2012-12-18       Impact factor: 3.312

2.  In Vitro Antifungal Activity of Ankaferd Blood Stopper Against Candida albicans.

Authors:  Sevgi Ciftci; Fahriye Keskin; Sema Keceli Ozcan; Mehmet Ali Erdem; Burak Cankaya; Recep Bingol; Cetin Kasapoglu
Journal:  Curr Ther Res Clin Exp       Date:  2011-06

3.  Potent Antifungal Activity of Pure Compounds from Traditional Chinese Medicine Extracts against Six Oral Candida Species and the Synergy with Fluconazole against Azole-Resistant Candida albicans.

Authors:  Zhimin Yan; Hong Hua; Yanying Xu; Lakshman P Samaranayake
Journal:  Evid Based Complement Alternat Med       Date:  2012-02-12       Impact factor: 2.629

4.  Synergistic Effects of Licorice Root and Walnut Leaf Extracts on Gastrointestinal Candidiasis, Inflammation and Gut Microbiota Composition in Mice.

Authors:  Hélène Authier; Valérie Bardot; Lucile Berthomier; Bénédicte Bertrand; Claude Blondeau; Sophie Holowacz; Agnès Coste
Journal:  Microbiol Spectr       Date:  2022-03-09

5.  Cytotoxicity of Brazilian plant extracts against oral microorganisms of interest to dentistry.

Authors:  Jonatas Rafael de Oliveira; Vinicius Carlos de Castro; Polyana das Graças Figueiredo Vilela; Samira Esteves Afonso Camargo; Cláudio Antonio Talge Carvalho; Antonio Olavo Cardoso Jorge; Luciane Dias de Oliveira
Journal:  BMC Complement Altern Med       Date:  2013-08-15       Impact factor: 3.659

Review 6.  Glycyrrhiza Genus: Enlightening Phytochemical Components for Pharmacological and Health-Promoting Abilities.

Authors:  Javad Sharifi-Rad; Cristina Quispe; Jesús Herrera-Bravo; Lisandra Herrera Belén; Rajandeep Kaur; Dorota Kregiel; Yadav Uprety; Ahmet Beyatli; Balakyz Yeskaliyeva; Celale Kırkın; Beraat Özçelik; Surjit Sen; Krishnendu Acharya; Farukh Sharopov; Natália Cruz-Martins; Manoj Kumar; Ahmad Faizal Abdull Razis; Usman Sunusi; Ramla Muhammad Kamal; Shabnum Shaheen; Hafiz Ansar Rasul Suleria
Journal:  Oxid Med Cell Longev       Date:  2021-07-24       Impact factor: 6.543
  6 in total

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