| Literature DB >> 19066838 |
S Krege1.
Abstract
Retroperitoneal lymph node dissection (RPLND) is an integral part in the therapy of nonseminomatous germ cell tumors. However, there has been a shift concerning the indication. For a long period RPLND was the primary choice in clinical stage I nonseminoma. Nowadays a risk-adapted strategy is preferred. RPLND is obligatory after finishing chemotherapy in metastasized patients if residual tumor is seen. In cases of a late relapse surgery is much more important than chemotherapy independent of increased tumor markers. RPLND can also be a salvage strategy in chemoresistant patients. About 25% of these patients have a long-term benefit. Open or laparoscopic surgery can be performed, though the indications for laparoscopy are small.Entities:
Mesh:
Year: 2009 PMID: 19066838 DOI: 10.1007/s00120-008-1757-7
Source DB: PubMed Journal: Urologe A ISSN: 0340-2592 Impact factor: 0.639