Literature DB >> 190657

Effect of paraquat on rat lung prolyl hydroxylase.

M A Hollinger, M Chvapil.   

Abstract

Acute administration of Paraquat (25 mg/kg, I.P.) was found to significantly increase prolyl hydroxylase in rat lung 7 days following treatment. There was no change in total collagen at this time point. At 21 days following drug treatment, total collagen was significantly elevated while prolyl hydroxylase activity had returned to control level.

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Year:  1977        PMID: 190657

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN: 0034-5164


  3 in total

1.  Collagen prolyl hydroxylase levels in experimental paraquat poisoning.

Authors:  W D Thompson; R S Patrick
Journal:  Br J Exp Pathol       Date:  1978-06

2.  Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat.

Authors:  M Griffin; L L Smith; J Wynne
Journal:  Br J Exp Pathol       Date:  1979-12

Review 3.  Paraquat: model for oxidant-initiated toxicity.

Authors:  J S Bus; J E Gibson
Journal:  Environ Health Perspect       Date:  1984-04       Impact factor: 9.031

  3 in total

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