OBJECTIVE: To confirm the presence of uveal effusion in the eyes of Asian patients with primary angle closure glaucoma (PACG) using ultrasound biomicroscopy (UBM). METHODS: In this observational case series, 70 patients with PACG (28 untreated patients with newly diagnosed PACG and 42 patients who had undergone previous laser iridotomy and were being monitored) and 12 patients with acute primary angle closure (APAC) were recruited. Eyes of patients with newly diagnosed PACG and APAC underwent UBM before and after laser iridotomy, whereas eyes of patients with treated PACG underwent UBM at enrollment. Uveal effusion was defined as a clear space between the choroid and sclera and was graded as follows: grade 0, none; grade 1, slitlike; grade 2, bandlike; and grade 3, obvious. RESULTS: Overall, uveal effusion was found in 11 of 70 eyes with PACG (15.7%; 95% confidence interval, 8.8%-26.2%) and in 3 of 12 eyes with APAC (25%; 95% confidence interval, 8.0%-53.4%). For patients with newly diagnosed PACG, uveal effusion was found in 4 of 28 eyes (14.2%; 95% confidence interval, 5.1%-32.1%) before laser iridotomy; 2 eyes had effusion after laser iridotomy. When present, the effusion was grade 1 in PACG eyes and grade 2 or 3 in APAC eyes. CONCLUSIONS: Uveal effusion was present in a significant proportion of Asian eyes with PACG and APAC, confirming a recent report of this finding.
OBJECTIVE: To confirm the presence of uveal effusion in the eyes of Asian patients with primary angle closure glaucoma (PACG) using ultrasound biomicroscopy (UBM). METHODS: In this observational case series, 70 patients with PACG (28 untreated patients with newly diagnosed PACG and 42 patients who had undergone previous laser iridotomy and were being monitored) and 12 patients with acute primary angle closure (APAC) were recruited. Eyes of patients with newly diagnosed PACG and APAC underwent UBM before and after laser iridotomy, whereas eyes of patients with treated PACG underwent UBM at enrollment. Uveal effusion was defined as a clear space between the choroid and sclera and was graded as follows: grade 0, none; grade 1, slitlike; grade 2, bandlike; and grade 3, obvious. RESULTS: Overall, uveal effusion was found in 11 of 70 eyes with PACG (15.7%; 95% confidence interval, 8.8%-26.2%) and in 3 of 12 eyes with APAC (25%; 95% confidence interval, 8.0%-53.4%). For patients with newly diagnosed PACG, uveal effusion was found in 4 of 28 eyes (14.2%; 95% confidence interval, 5.1%-32.1%) before laser iridotomy; 2 eyes had effusion after laser iridotomy. When present, the effusion was grade 1 in PACG eyes and grade 2 or 3 in APAC eyes. CONCLUSIONS:Uveal effusion was present in a significant proportion of Asian eyes with PACG and APAC, confirming a recent report of this finding.
Authors: Eugenio A Maul; David S Friedman; Dolly S Chang; Michael V Boland; Pradeep Y Ramulu; Henry D Jampel; Harry A Quigley Journal: Ophthalmology Date: 2011-04-13 Impact factor: 12.079
Authors: Henrietta Ho; Mineo Ozaki; Takanori Mizoguchi; Shamira A Perera; Daniel H Su; Mingguang He; Tien Y Wong; Monisha E Nongpiur; Tin Aung Journal: Graefes Arch Clin Exp Ophthalmol Date: 2015-02-01 Impact factor: 3.117
Authors: K Saidas Nair; Mounira Hmani-Aifa; Zain Ali; Alison L Kearney; Salma Ben Salem; Danilo G Macalinao; Ioan M Cosma; Walid Bouassida; Bochra Hakim; Zeineb Benzina; Ileana Soto; Peter Söderkvist; Gareth R Howell; Richard S Smith; Hammadi Ayadi; Simon W M John Journal: Nat Genet Date: 2011-05-01 Impact factor: 38.330