Literature DB >> 19064319

Syntheses and evaluation of glucosyl aryl thiosemicarbazide and glucosyl thiosemicarbazone derivatives as antioxidant and anti-dyslipidemic agents.

Samir Ghosh1, Anup Kumar Misra, Gitika Bhatia, M M Khan, A K Khanna.   

Abstract

A series of N-per-O-acetyl-glucosyl arylthiosemicarbazide and thiosemicarbazone derivatives have been synthesized and evaluated for their in vivo anti-dyslipidemic and in vitro antioxidant activities. Among 16 compounds tested, 3 compounds showed potent anti-dyslipidemic activity and 6 compounds showed potent antioxidant and scavenger of oxygen free radicals activity.

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Year:  2008        PMID： 19064319     DOI： 10.1016/j.bmcl.2008.11.070

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  6 in total

1.  1-(4-Ethoxy-benzo-yl)-4-(4-methoxy-phen-yl)thiosemicarbazide.

Authors:  Saira Khanum; Muhammad Farman; Nasim H Rama; Shahid Hameed; Peter G Jones
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-10-03

2.  A new synthetic access to 2-N-(glycosyl)thiosemicarbazides from 3-N-(glycosyl)oxadiazolinethiones and the regioselectivity of the glycosylation of their oxadiazolinethione precursors.

Authors:  El Sayed H El Ashry; El Sayed H El Tamany; Mohy El Din Abdel Fattah; Mohamed R E Aly; Ahmed T A Boraei; Axel Duerkop
Journal:  Beilstein J Org Chem       Date:  2013-01-21       Impact factor: 2.883

3.  Conjugated Oligo-Aromatic Compounds Bearing a 3,4,5-Trimethoxy Moiety: Investigation of Their Antioxidant Activity Correlated with a DFT Study.

Authors:  Huda S Kareem; Nurdiana Nordin; Thorsten Heidelberg; Azlina Abdul-Aziz; Azhar Ariffin
Journal:  Molecules       Date:  2016-02-17       Impact factor: 4.411

4.  Synthesis, Structure and Antioxidant Activity of (Tetra-O-acetyl-β-D-galactopyranosyl)thiosemicarbazones of Substituted Benzaldehydes.

Authors:  Nguyen D Thanh; Le T Hoai
Journal:  Indian J Pharm Sci       Date:  2012-01       Impact factor: 0.975

5.  Synthesis and antibacterial and antifungal activities of N-(tetra-O-acetyl-β-d-glucopyranosyl)thiosemicarbazones of substituted 4-formylsydnones.

Authors:  Nguyen Dinh Thanh; Hoang Thanh Duc; Vu Thi Duyen; Phan Manh Tuong; Nguyen Van Quoc
Journal:  Chem Cent J       Date:  2015-10-19       Impact factor: 4.215

6.  Synthesis and Bioactivity of Thiosemicarbazones Containing Adamantane Skeletons.

Authors:  Van Hien Pham; Thi Phuong Dung Phan; Dinh Chau Phan; Binh Duong Vu
Journal:  Molecules       Date:  2020-01-13       Impact factor: 4.411
  6 in total

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