| Literature DB >> 19063948 |
B Piallat1, S Chabardès, N Torres, V Fraix, L Goetz, E Seigneuret, E Bardinet, M Ferraye, B Debu, P Krack, J Yelnik, P Pollak, A L Benabid.
Abstract
In animals, the pedunculopontine (PPN) and the sub-cuneiform (SCU) nuclei located in the upper brainstem are involved during the processing of gait. Similar functional nuclei are suspected in humans but their role in gait is unclear. Here we show that, using extra-cellular recordings of the PPN/SCU region obtained in two parkinsonian patients, the SCU neurons increased their firing rate without modifying their firing pattern during mimicked steps. We conclude that SCU neurons are activated during gait processes.Entities:
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Year: 2008 PMID： 19063948 DOI： 10.1016/j.neuroscience.2008.10.046
Source DB: PubMed Journal: Neuroscience ISSN： 0306-4522 Impact factor: 3.590