Literature DB >> 19062663

Laparoscopic cholecystectomy for treatment of biliary dyskinesia is safe and effective in the pediatric population.

Matthew Hofeldt1, Bryan Richmond, Kristy Huffman, Jennings Nestor, Damian Maxwell.   

Abstract

Experience with laparoscopic cholecystectomy for biliary dyskinesia in children remains limited. The aim of this study was to examine the results of a single institution's experience with laparoscopic cholecystectomy for the treatment biliary dyskinesia in the pediatric population. Medical records were reviewed on all patients younger than age 18 who underwent laparoscopic cholecystectomy at our institution from July 2004 to December 2006. Patients undergoing surgery for biliary dyskinesia, as evidenced by a preoperative gallbladder ejection fraction of 40 per cent or less, comprised the study group. Of the 51 pediatric laparoscopic cholecystectomies, 30 (58.8%) were performed for biliary dyskinesia. The patients' ages ranged from 7 to 17 (mean, 12.67 years; SD, 2.75). Symptoms consisted of chronic right upper quadrant pain (96.67%), nausea/vomiting (73.33%), back pain (30.0%), weight loss (13.33%), and a history of pancreatitis (6.66%). The amount of time between onset of symptoms and surgery was as follows: 1 to 3 months (34.62%), 4 to 6 months (30.77%), 7 to 12 months (7.69%), and greater than 1 year (26.92%). Gallbladder ejection fraction ranged from 1 to 36 per cent (mean, 14.7%). Seven of the 30 (26.67%) underwent endoscopic evaluation as part of their preoperative workup (six upper endoscopy, one colonoscopy), all of which were noncontributory. Pathology revealed chronic cholecystitis in 26 of 30 (93.3%), no abnormalities in three of 30 (10.0%), and unexpected cholelithiasis in one of 30 (3.33%). No perioperative complications were encountered. Twenty-nine of the 30 patients were available for follow up and all but one reported relief of symptoms (96.55%). This study supports the use of laparoscopic cholecystectomy as a safe and effective treatment for biliary dyskinesia in the pediatric population. The success rate in our study was substantially higher than that reported in previous series. Routine preoperative endoscopy was not used and was reserved for investigation of ambiguous or unrelated complaints.

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Year:  2008        PMID: 19062663

Source DB:  PubMed          Journal:  Am Surg        ISSN: 0003-1348            Impact factor:   0.688


  14 in total

1.  Pediatric cholecystectomy for symptomatic gallstones unrelated to hematologic disorder.

Authors:  Sang Gyun Suh; Yoo-Shin Choi; Kwi-Won Park; Seung Eun Lee
Journal:  Ann Hepatobiliary Pancreat Surg       Date:  2016-11-30

2.  Evaluation of gastrointestinal pathology and treatment in children with suspected biliary dyskinesia.

Authors:  Wikrom Karnsakul; Richard Vaughan; Tarun Kumar; Stacey Gillespie; Kathryn Skitarelic
Journal:  Pediatr Surg Int       Date:  2011-06-25       Impact factor: 1.827

Review 3.  Cholecystectomy for biliary dyskinesia: how did we get there?

Authors:  Klaus Bielefeldt; Shreyas Saligram; Susan L Zickmund; Anwar Dudekula; Mojtaba Olyaee; Dhiraj Yadav
Journal:  Dig Dis Sci       Date:  2014-09-06       Impact factor: 3.199

Review 4.  Biliary disease in children.

Authors:  Matthew Goldman; Thomas Pranikoff
Journal:  Curr Gastroenterol Rep       Date:  2011-04

5.  Biliary dyskinesia: how effective is cholecystectomy?

Authors:  Vikas Singhal; Patrick Szeto; Heather Norman; Nan Walsh; Burt Cagir; Thomas J VanderMeer
Journal:  J Gastrointest Surg       Date:  2011-11-01       Impact factor: 3.452

6.  Biliary dyskinesia and symptomatic gallstone disease in children: two sides of the same coin?

Authors:  Arvind I Srinath; Ada O Youk; Klaus Bielefeldt
Journal:  Dig Dis Sci       Date:  2014-04-09       Impact factor: 3.199

7.  Regional differences in hospitalizations and cholecystectomies for biliary dyskinesia.

Authors:  Klaus Bielefeldt
Journal:  J Neurogastroenterol Motil       Date:  2013-07-08       Impact factor: 4.924

8.  Diagnostic stringency and healthcare needs in patients with biliary dyskinesia.

Authors:  Nitin Aggarwal; Klaus Bielefeldt
Journal:  Dig Dis Sci       Date:  2013-08-11       Impact factor: 3.199

9.  Biliary Tract Disease in Girls and Young Women With Rett Syndrome.

Authors:  Kathleen J Motil; Jane B Lane; Judy O Barrish; Fran Annese; Suzanne Geerts; Lauren McNair; Steven A Skinner; Jeffrey L Neul; Daniel G Glaze; Alan K Percy
Journal:  J Pediatr Gastroenterol Nutr       Date:  2019-06       Impact factor: 2.839

10.  Pilot Randomized Controlled Trial of Laparoscopic Cholecystectomy vs Active Nonoperative Therapy for the Treatment of Biliary Dyskinesia.

Authors:  Bryan K Richmond; Caresse Grodman; Jerri Walker; Scott Dean; Edward H Tiley; Roland E Hamrick; Kristen Statler; Mary Emmett
Journal:  J Am Coll Surg       Date:  2016-03-11       Impact factor: 6.113

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