INTRODUCTION: Cystic fibrosis afflicted lungs support the growth of many bacteria rarely implicated in other cases of human infections. CASE PRESENTATION: We report the isolation and identification, by 16S rRNA amplification and sequencing, of two emerging pathogens resistant to colistin, Brevundimonas diminuta and Ochrobactrum anthropi, in a 17-year-old woman with cystic fibrosis and pneumonia. The patient eventually responded well to a 2-week regime of imipenem and tobramycin. CONCLUSION: Our results clearly re-emphasize the emergence of new colistin-resistant pathogens in patients with cystic fibrosis.
INTRODUCTION:Cystic fibrosis afflicted lungs support the growth of many bacteria rarely implicated in other cases of humaninfections. CASE PRESENTATION: We report the isolation and identification, by 16S rRNA amplification and sequencing, of two emerging pathogens resistant to colistin, Brevundimonas diminuta and Ochrobactrum anthropi, in a 17-year-old woman with cystic fibrosis and pneumonia. The patient eventually responded well to a 2-week regime of imipenem and tobramycin. CONCLUSION: Our results clearly re-emphasize the emergence of new colistin-resistant pathogens in patients with cystic fibrosis.
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