Literature DB >> 190610

Lipokinetic studies with gemfibrozil (CI-719).

A H Kissebah, P A Adams, V Wynn.   

Abstract

Gemfibrozil (CI-719) has proved to be an effective agent in reducing the plasma triglyceride levels in experimental animals and in patients with endogenous hypertriglyceridaemia. We have confirmed these findings.

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Year:  1976        PMID： 190610      PMCID： PMC1864040     

Source DB:  PubMed          Journal:  Proc R Soc Med        ISSN： 0035-9157


  8 in total

1.  Metabolism of rat plasma very low density lipoprotein. I. Fate in circulation of the whole lipoprotein.

Authors:  S Eisenberg; D Rachmilewitz
Journal:  Biochim Biophys Acta       Date:  1973-12-20

2.  Precursors of plasma triglyceride fatty acids in obesity.

Authors:  P J Barter; P J Nestel
Journal:  Metabolism       Date:  1973-06       Impact factor: 8.694

3.  Plasma free fatty acid and triglyceride transport kinetics in man.

Authors:  A H Kissebah; P W Adams; V Wynn
Journal:  Clin Sci Mol Med       Date:  1974-09

4.  The kinetics of plasma free fatty acid and triglyceride transport in patients with idiopathic hypertriglyceridaemia and their relation to carbohydrate metabolism.

Authors:  P W Adams; A H Kissebah; P Harrigan; T Stokes; V Wynn
Journal:  Eur J Clin Invest       Date:  1974-06       Impact factor: 4.686

5.  Precursors of plasma triglyceride fatty acid in humans. Effects of glucose consumption, clofibrate administration, and alcoholic fatty liver.

Authors:  P J Barter; P J Nestel; K F Carroll
Journal:  Metabolism       Date:  1972-02       Impact factor: 8.694

6.  The mechanism of action of clofibrate and tetranicotinoylfructose (Bradilan) on the kinetics of plasma free fatty acid and triglyceride transport in type IV and type V hypertriglyceridaemia.

Authors:  A H Kissebah; P W Adams; P Harrigan; V Wynn
Journal:  Eur J Clin Invest       Date:  1974-06       Impact factor: 4.686

7.  Transport kinetics of plasma free fatty acid, very low density lipoprotein triglycerides and apoprotein in patients with endogenous hypertriglyceridaemia: effects of 2,2-dimethyl, 5(2, 5-xylyoxy) valeric acid therapy.

Authors:  A H Kissebah; S Alfarsi; P W Adams; M Seed; J Folkard; V Wynn
Journal:  Atherosclerosis       Date:  1976 Jul-Aug       Impact factor: 5.162

8.  The metabolic fate of plasma lipoproteins in normal subjects and in patients with insulin resistance and endogenous hypertriglyceridaemia.

Authors:  A H Kissebah; S Alfarsi; P W Adams; V Wynn
Journal:  Diabetologia       Date:  1976-10       Impact factor: 10.122
  8 in total
  2 in total

Review 1.  Gemfibrozil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in dyslipidaemia.

Authors:  P A Todd; A Ward
Journal:  Drugs       Date:  1988-09       Impact factor: 9.546

2.  Lowering of triglycerides by gemfibrozil affects neither the glucoregulatory nor antilipolytic effect of insulin in type 2 (non-insulin-dependent) diabetic patients.

Authors:  H Vuorinen-Markkola; H Yki-Järvinen; M R Taskinen
Journal:  Diabetologia       Date:  1993-02       Impact factor: 10.122
  2 in total

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