Literature DB >> 19060727

Epidemiology and outcomes of older adults with burn injury: an analysis of the National Burn Repository.

Tam N Pham1, C Bradley Kramer, Jin Wang, Frederick P Rivara, David M Heimbach, Nicole S Gibran, Matthew B Klein.   

Abstract

Improvements in outcomes for older adults sustaining burn injuries have lagged far behind those of younger patients. As this segment of the population grows, there has been an increasing interest in better understanding the epidemiology and outcomes of injury in older adults. The National Burn Repository (NBR) provides a unique opportunity to examine burn injuries on a national level. We aimed to characterize specific injury and outcome trends in older adult with burns through analysis of the NBR. We examined the records of all patients in the NBR aged 55 and older. To characterize age effects on injury and outcomes, patients were stratified into three age categories: 55 to 64 years, 65 to 74 years, and 75 years and older. Baseline characteristics, details of hospital treatment, mortality, and disposition were compared among these three age groups using chi or analysis of variance. Logistic regression analysis was performed to assess the impact of age on burn mortality. A total of 180,401 patient records were available from 1991 to 2005, of which 23,180 (14%) met age inclusion criteria. Mean burn size (9.6% TBSA) and percent with inhalation injury (11.3%) did not markedly differ by age. Men predominated overall (ratio 1.4:1), although women (4290) outnumbered men (3439) in the oldest age category. Length of stay per TBSA and median hospital charges increased with increasing age category, suggesting higher resource consumption with aging. Mean number of operations per patient, however, decreased with age. Mortality rates and discharge to nonindependent status increased with age. By logistic regression, the adjusted odds ratio for mortality was 2.3 (95% CI 2.1-2.7) in the 65 to 74 age group, and 5.4 (95% CI 4.8-6.1) in the oldest group when compared with the 55 to 64 age group. Mortality rates decreased significantly after 2001 across all age groups. This analysis demonstrates age-dependent differences in resource utilization and mortality risk within the older burn population and highlights the need for a national research agenda focused on management practices and outcomes in older adult with burns.

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Year:  2009        PMID: 19060727      PMCID: PMC3042349          DOI: 10.1097/BCR.0b013e3181921efc

Source DB:  PubMed          Journal:  J Burn Care Res        ISSN: 1559-047X            Impact factor:   1.845


  28 in total

1.  Long-term trends in mortality according to age among adult burn patients.

Authors:  Gerald McGwin; James M Cross; Jeremy W Ford; Loring W Rue
Journal:  J Burn Care Rehabil       Date:  2003 Jan-Feb

2.  Causes of death and predictors in burned patients more than 60 years of age.

Authors:  M M Anous; D M Heimbach
Journal:  J Trauma       Date:  1986-02

3.  The continuing challenge of burn care in the elderly.

Authors:  J R Saffle; C M Larson; J Sullivan; J Shelby
Journal:  Surgery       Date:  1990-09       Impact factor: 3.982

4.  Surgical treatment of burns in elderly patients.

Authors:  J J Burdge; B Katz; R Edwards; R Ruberg
Journal:  J Trauma       Date:  1988-02

5.  Multifactorial probit analysis of mortality in burned patients.

Authors:  B E Zawacki; S P Azen; S H Imbus; Y T Chang
Journal:  Ann Surg       Date:  1979-01       Impact factor: 12.969

6.  Prediction of burn mortality.

Authors:  J Tobiasen; J H Hiebert; R F Edlich
Journal:  Surg Gynecol Obstet       Date:  1982-05

7.  The abbreviated burn severity index.

Authors:  J Tobiasen; J M Hiebert; R F Edlich
Journal:  Ann Emerg Med       Date:  1982-05       Impact factor: 5.721

8.  Increased survival after major thermal injury. A nine year review.

Authors:  S W Merrell; J R Saffle; J J Sullivan; C M Larsen; G D Warden
Journal:  Am J Surg       Date:  1987-12       Impact factor: 2.565

9.  Admissions across state lines: harnessing the insight of the National Burn Repository for the healthcare accessibility, fiscal, and legislative concerns facing the American Burn Association.

Authors:  Mark F Guagliardo; James C Jeng; Susan Browning; Mary-Elizabeth Bilodeau; Alan Dimick; William Hickerson; Sidney Miller; Michael Peck
Journal:  J Burn Care Res       Date:  2008 Jan-Feb       Impact factor: 1.845

10.  A policy of early excision and grafting in elderly burn patients shortens the hospital stay and improves survival.

Authors:  E A Deitch
Journal:  Burns Incl Therm Inj       Date:  1985-12
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  36 in total

1.  Aging and the pathogenic response to burn.

Authors:  Meenakshi Rani; Martin G Schwacha
Journal:  Aging Dis       Date:  2011-07-04       Impact factor: 6.745

2.  Amputation Following Burn Injury.

Authors:  Colleen N Bartley; Kenisha Atwell; Laura Purcell; Bruce Cairns; Anthony Charles
Journal:  J Burn Care Res       Date:  2019-06-21       Impact factor: 1.845

3.  Aging impairs the mobilization and homing of bone marrow-derived angiogenic cells to burn wounds.

Authors:  Xianjie Zhang; Kakali Sarkar; Sergio Rey; Raul Sebastian; Efstathia Andrikopoulou; Guy P Marti; Karen Fox-Talbot; Gregg L Semenza; John W Harmon
Journal:  J Mol Med (Berl)       Date:  2011-04-16       Impact factor: 4.599

4.  Age-related immune responses after burn and inhalation injury are associated with altered clinical outcomes.

Authors:  John H Frankel; Devin M Boe; Joslyn M Albright; Eileen B O'Halloran; Stewart R Carter; Christopher S Davis; Luis Ramirez; Ellen L Burnham; Richard L Gamelli; Majid Afshar; Elizabeth J Kovacs
Journal:  Exp Gerontol       Date:  2017-10-26       Impact factor: 4.032

5.  High voltage electrical injury: an 11-year single center epidemiological study.

Authors:  B Lipový; Y Kaloudová; H Ríhová; Z Chaloupková; T Kempný; I Suchanek; P Brychta
Journal:  Ann Burns Fire Disasters       Date:  2014-06-30

6.  Diabetes does not influence selected clinical outcomes in critically ill burn patients.

Authors:  Chaitanya K Dahagam; Alejandra Mora; Steven E Wolf; Charles E Wade
Journal:  J Burn Care Res       Date:  2011 Mar-Apr       Impact factor: 1.845

Review 7.  Recent trends in burn epidemiology worldwide: A systematic review.

Authors:  Christian Smolle; Janos Cambiaso-Daniel; Abigail A Forbes; Paul Wurzer; Gabriel Hundeshagen; Ludwik K Branski; Fredrik Huss; Lars-Peter Kamolz
Journal:  Burns       Date:  2016-09-03       Impact factor: 2.744

Review 8.  The biochemical alterations underlying post-burn hypermetabolism.

Authors:  Christopher Auger; Osai Samadi; Marc G Jeschke
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2017-02-20       Impact factor: 5.187

9.  IL-6 Signal From the Bone Marrow is Required for the Browning of White Adipose Tissue Post Burn Injury.

Authors:  Abdikarim Abdullahi; Peter Chen; Mile Stanojcic; Ali-Reza Sadri; Natalie Coburn; Marc G Jeschke
Journal:  Shock       Date:  2017-01       Impact factor: 3.454

10.  Evidence for simvastatin anti-inflammatory actions based on quantitative analyses of NETosis and other inflammation/oxidation markers.

Authors:  Walid M Al-Ghoul; Margarita S Kim; Nadeem Fazal; Anser C Azim; Ashraf Ali
Journal:  Results Immunol       Date:  2014-03-25
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