| Literature DB >> 1906010 |
Abstract
Exposure of hamster amelanotic melanoma cells to L-tyrosine caused a time-dependent increase of tyrosinase protein concentrations, tyrosinase activity and level of cell pigmentation. In contrast, Northern blot analysis using mouse tyrosinase cDNA showed a steady level of tyrosinase mRNA. Thus in hamster melanoma cells the stimulation of intracellular tyrosinase concentration by L-tyrosine is mediated mainly via a posttranscriptional mechanism.Entities:
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Year: 1991 PMID: 1906010 DOI: 10.1007/bf01958826
Source DB: PubMed Journal: Experientia ISSN: 0014-4754