Literature DB >> 19059061

Dynamic pharmacogenetic models in anticoagulation therapy.

Marjorie Bon Homme1, Kristen K Reynolds, Roland Valdes, Mark W Linder.   

Abstract

This article demonstrates how a dynamic clinical-support tool can guide individualized drug therapy. We use the drug warfarin as a model to demonstrate how pharmacogenetics when combined with fundamental principles of pharmacokinetic and pharmacodynamics can provide a powerful decision-support tool to optimize personalized therapeutics.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 19059061     DOI： 10.1016/j.cll.2008.10.002

Source DB:  PubMed          Journal:  Clin Lab Med        ISSN： 0272-2712            Impact factor:   1.935


  5 in total

Review 1.  Clinical decision support for genetically guided personalized medicine: a systematic review.

Authors:  Brandon M Welch; Kensaku Kawamoto
Journal:  J Am Med Inform Assoc       Date:  2012-08-25       Impact factor: 4.497

2.  Genotyping three SNPs affecting warfarin drug response by isothermal real-time HDA assays.

Authors:  Ying Li; Saeed A Jortani; Bronwyn Ramey-Hartung; Elizabeth Hudson; Bertrand Lemieux; Huimin Kong
Journal:  Clin Chim Acta       Date:  2010-09-18       Impact factor: 3.786

3.  Prospective pilot trial of PerMIT versus standard anticoagulation service management of patients initiating oral anticoagulation.

Authors:  Mark P Borgman; Robert C Pendleton; Gwendolyn A McMillin; Kristen K Reynolds; Sara Vazquez; Andrew Freeman; Andrew Wilson; Roland Valdes; Mark W Linder
Journal:  Thromb Haemost       Date:  2012-07-26       Impact factor: 5.249

4.  Warfarin anticoagulant therapy: a Southern Italy pharmacogenetics-based dosing model.

Authors:  Cristina Mazzaccara; Valeria Conti; Rosario Liguori; Vittorio Simeon; Mario Toriello; Angelo Severini; Corrado Perricone; Alfonso Meccariello; Pasquale Meccariello; Dino Franco Vitale; Amelia Filippelli; Lucia Sacchetti
Journal:  PLoS One       Date:  2013-08-26       Impact factor: 3.240

5.  The need for clinical decision support integrated with the electronic health record for the clinical application of whole genome sequencing information.

Authors:  Brandon M Welch; Kensaku Kawamoto
Journal:  J Pers Med       Date:  2013-12-18
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.