Literature DB >> 19058965

Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives.

Julie Charton1, Rebecca Deprez-Poulain, Nathalie Hennuyer, Anne Tailleux, Bart Staels, Benoit Deprez.   

Abstract

We have successfully obtained 1,2,4-oxadiazol-5-one bioisoteres of Am580 or Tazarotene-like retinoids. In particular compound 4 displays an EC(50) of 26nM on RAR-beta.

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Year:  2008        PMID： 19058965     DOI： 10.1016/j.bmcl.2008.11.040

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

1.  Retinoic acid has different effects on UCP1 expression in mouse and human adipocytes.

Authors:  Maria Murholm; Marie S Isidor; Astrid L Basse; Sally Winther; Cathrine Sørensen; Jonas Skovgaard-Petersen; Maja M Nielsen; Aina S Hansen; Bjørn Quistorff; Jacob B Hansen
Journal:  BMC Cell Biol       Date:  2013-09-23       Impact factor: 4.241

Review 2.  Trifarotene: A Current Review and Perspectives in Dermatology.

Authors:  Terenzio Cosio; Monia Di Prete; Roberta Gaziano; Caterina Lanna; Augusto Orlandi; Paolo Di Francesco; Luca Bianchi; Elena Campione
Journal:  Biomedicines       Date:  2021-02-26

3.  Development of 1,2,4-Oxadiazole Antimicrobial Agents to Treat Enteric Pathogens within the Gastrointestinal Tract.

Authors:  Noel P Pitcher; Jitendra R Harjani; Yichao Zhao; Jianwen Jin; Daniel R Knight; Lucy Li; Papanin Putsathit; Thomas V Riley; Glen P Carter; Jonathan B Baell
Journal:  ACS Omega       Date:  2022-02-18

4.  Molluscan RXR Transcriptional Regulation by Retinoids in a Drosophila CNS Organ Culture System.

Authors:  Eric de Hoog; Victoria Elda Saba Echezarreta; Anel Turgambayeva; Gregory Foran; Marvel Megaly; Aleksandar Necakov; Gaynor E Spencer
Journal:  Cells       Date:  2022-08-11       Impact factor: 7.666
  4 in total

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