Literature DB >> 19058776

Isolation and production of cells suitable for human therapy: challenges ahead.

Lars Ahrlund-Richter1, Michele De Luca, Daniel R Marshak, Megan Munsie, Anna Veiga, Mahendra Rao.   

Abstract

Considerable practical hurdles must be overcome prior to the broad application of stem cell therapies. We outline challenges that may vary across different models of cell therapy, including the following broad concepts: issues related to the sourcing of material, and issues related to product manufacturing, shipping, storage and tracking, and standardization.

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Mesh：

Year:  2008        PMID： 19058776     DOI： 10.1016/j.stem.2008.11.012

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  40 in total

1.  Micromanipulation of culture niche permits long-term expansion of dental pulp stem cells--an economic and commercial angle.

Authors:  Vijayendran Govindasamy; Veronica Sainik Ronald; Swapnil Totey; Salina Binti Din; Wan Mahadzir Bin Wan Mustafa; Satish Totey; Zubaidah Zakaria; Ramesh R Bhonde
Journal:  In Vitro Cell Dev Biol Anim       Date:  2010-08-20       Impact factor: 2.416

2.  Derivation, Expansion, and Motor Neuron Differentiation of Human-Induced Pluripotent Stem Cells with Non-Integrating Episomal Vectors and a Defined Xenogeneic-free Culture System.

Authors:  Wentao Hu; Yongpei He; Yongjie Xiong; Hong Lu; Hong Chen; Limin Hou; Zhandong Qiu; Yu Fang; Suming Zhang
Journal:  Mol Neurobiol       Date:  2015-02-10       Impact factor: 5.590

3.  Cell therapy: cGMP facilities and manufacturing.

Authors:  Raffaella Giancola; Tiziana Bonfini; Antonio Iacone
Journal:  Muscles Ligaments Tendons J       Date:  2012-10-16

4.  Clinical grade adult stem cell banking.

Authors:  Sreedhar Thirumala; W Scott Goebel; Erik J Woods
Journal:  Organogenesis       Date:  2009-07       Impact factor: 2.500

Review 5.  Application of biomaterials to advance induced pluripotent stem cell research and therapy.

Authors:  Zhixiang Tong; Aniruddh Solanki; Allison Hamilos; Oren Levy; Kendall Wen; Xiaolei Yin; Jeffrey M Karp
Journal:  EMBO J       Date:  2015-03-12       Impact factor: 11.598

Review 6.  Ethical development of stem-cell-based interventions.

Authors:  Amanda MacPherson; Jonathan Kimmelman
Journal:  Nat Med       Date:  2019-07-03       Impact factor: 53.440

7.  Chinese newspaper coverage of (unproven) stem cell therapies and their providers.

Authors:  Ubaka Ogbogu; Li Du; Christen Rachul; Lisa Bélanger; Timothy Caulfield
Journal:  Stem Cell Rev Rep       Date:  2013-04       Impact factor: 5.739

8.  Harmonizing standards for producing clinical-grade therapies from pluripotent stem cells.

Authors:  Peter W Andrews; Joy Cavagnaro; Joy Cavanagro; Robert Deans; Ellen Feigal; Ellen Feigel; Ed Horowitz; Armand Keating; Mahendra Rao; Marc Turner; Ian Wilmut; Shinya Yamanaka
Journal:  Nat Biotechnol       Date:  2014-08       Impact factor: 54.908

9.  Musings on genome medicine: is there hope for ethical and safe stem cell therapeutics?

Authors:  Mahendra Rao; Maureen L Condic
Journal:  Genome Med       Date:  2009-07-14       Impact factor: 11.117

10.  Xeno-free defined conditions for culture of human embryonic stem cells, neural stem cells and dopaminergic neurons derived from them.

Authors:  Andrzej Swistowski; Jun Peng; Yi Han; Anna Maria Swistowska; Mahendra S Rao; Xianmin Zeng
Journal:  PLoS One       Date:  2009-07-14       Impact factor: 3.240
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