Literature DB >> 19057761

Glycosylated asterisks are among the most potent low valency inducers of Concanavalin A aggregation.

Mazen Sleiman1, Annabelle Varrot, Jean-Manuel Raimundo, Marc Gingras, Peter G Goekjian.   

Abstract

A new class of sulfurated, semi-rigid, radial and low-valent glycosylated asterisk ligands with potential dual function as ligand and probe has some of the highest inhibition potencies of Con A-induced hemagglutination, by using a cross-linking mechanism of Con A which amplifies the enhancement to near nanomolar concentrations with the alpha-d-mannose asterisk.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 19057761     DOI： 10.1039/b814816c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

Review 1.  Design and creativity in synthesis of multivalent neoglycoconjugates.

Authors:  Yoann M Chabre; René Roy
Journal:  Adv Carbohydr Chem Biochem       Date:  2010       Impact factor: 12.200

2.  Hexaphenylbenzene as a rigid template for the straightforward syntheses of "star-shaped" glycodendrimers.

Authors:  Yoann M Chabre; Patrick P Brisebois; Leïla Abbassi; Sheena C Kerr; John V Fahy; Isabelle Marcotte; René Roy
Journal:  J Org Chem       Date:  2010-12-29       Impact factor: 4.354

3.  Effect of Dendrimer Generation and Aglyconic Linkers on the Binding Properties of Mannosylated Dendrimers Prepared by a Combined Convergent and Onion Peel Approach.

Authors:  Celia Sehad; Tze Chieh Shiao; Lamyaa M Sallam; Abdelkrim Azzouz; René Roy
Journal:  Molecules       Date:  2018-07-28       Impact factor: 4.411

4.  Persulfurated Benzene-Cored Asterisks with π-Extended ThioNaphthyl Arms: Synthesis, Structural, Photophysical and Covalent Dynamic Properties.

Authors:  Sapna Gahlot; Alessandro Gradone; Myriam Roy; Michel Giorgi; Simone Conti; Paola Ceroni; Marco Villa; Marc Gingras
Journal:  Chemistry       Date:  2022-06-27       Impact factor: 5.020

5.  Expeditive synthesis of trithiotriazine-cored glycoclusters and inhibition of Pseudomonas aeruginosa biofilm formation.

Authors:  Meriem Smadhi; Sophie de Bentzmann; Anne Imberty; Marc Gingras; Raoudha Abderrahim; Peter G Goekjian
Journal:  Beilstein J Org Chem       Date:  2014-08-25       Impact factor: 2.883
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.