Literature DB >> 19056443

Simplifying paediatric immunization with a fully liquid DTP-HepB-Hib combination vaccine: evidence from a comparative time-motion study in India.

Karin A Wiedenmayer1, Svenja Weiss, Chandon Chattopadhyay, Ajoy Mukherjee, Ritabrata Kundu, Raffael Ayé, Fabrizio Tediosi, Manuel W Hetzel, Marcel Tanner.   

Abstract

An observational time-motion study investigated logistic, programmatic and safety-related advantages and limits in the delivery of a fully liquid DTP-HepB-Hib combination vaccine versus a lyophilized combination vaccine requiring reconstitution. The study was conducted in 2006, observing 312 child vaccinations in a tertiary hospital setting in Kolkata, India. The time for vaccination was on average 46s (35.12%) lower with the fully liquid vaccine (p<0.05). In addition, the fully liquid combination was easier and potentially safer to handle and as well tolerated as the lyophilized formulation. Fully liquid combination vaccines have the potential to simplify immunization schedules, contribute to better resource management and improve efficiency of immunization programs.

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Year:  2008        PMID： 19056443     DOI： 10.1016/j.vaccine.2008.11.045

Source DB:  PubMed          Journal:  Vaccine        ISSN： 0264-410X            Impact factor:   3.641


  10 in total

1.  Hexavalent vaccines: characteristics of available products and practical considerations from a panel of Italian experts.

Authors:  A Orsi; C Azzari; E Bozzola; G Chiamenti; G Chirico; S Esposito; F Francia; P Lopalco; R Prato; R Russo; A Villani; E Franco
Journal:  J Prev Med Hyg       Date:  2018-06-01

2.  Lot-to-lot consistency study of the fully liquid pentavalent DTwP-HepB-Hib vaccine Quinvaxem (®) demonstrating clinical equivalence, suitability of the vaccine as a booster and concomitant administration with measles vaccine.

Authors:  Sanet Aspinall; Deirdre Traynor; Philip Bedford; Katharina Hartmann
Journal:  Hum Vaccin Immunother       Date:  2012-08-01       Impact factor: 3.452

3.  DTaP(5)-IPV-Hib vaccine (Pediacel®).

Authors:  James E Frampton
Journal:  Paediatr Drugs       Date:  2011-12-01       Impact factor: 3.022

4.  Preferences of healthcare professionals regarding hexavalent pediatric vaccines in Italy: a survey of attitudes and expectations.

Authors:  Giancarlo Icardi; Andrea Orsi; Giovanni Vitali Rosati; Alessia Tognetto; Giovanni Checcucci Lisi; Salvatore Parisi
Journal:  J Prev Med Hyg       Date:  2020-10-06

5.  Hidden efficiencies: making completion of the pediatric vaccine schedule more efficient for physicians.

Authors:  Mike Ciarametaro; Steven E Bradshaw; Jillian Guiglotto; Beth Hahn; Genevieve Meier
Journal:  Medicine (Baltimore)       Date:  2015-01       Impact factor: 1.889

6.  Safety, immune lot-to-lot consistency and non-inferiority of a fully liquid pentavalent DTwp-HepB-Hib vaccine in healthy Indian toddlers and infants.

Authors:  Dulari J Gandhi; Sangappa M Dhaded; Mandyam D Ravi; Anand P Dubey; Ritabrata Kundu; Sanjay K Lalwani; Jugesh Chhatwal; Leni G Mathew; Madhu Gupta; Shiv D Sharma; Sandeep B Bavdekar; Midde V Jayanth; Suresh Ravinuthala; Arijit Sil; Mandeep S Dhingra
Journal:  Hum Vaccin Immunother       Date:  2015-11-18       Impact factor: 3.452

7.  Time and labour costs of preventive health care, including vaccinations, in Finnish child health clinics.

Authors:  Heta Nieminen; Tuovi Hakulinen; Taneli Puumalainen; Päivi Sirén; Arto A Palmu
Journal:  PLoS One       Date:  2022-10-03       Impact factor: 3.752

Review 8.  What are the preferences of health care professionals in Germany regarding fully liquid, ready-to-use hexavalent pediatric vaccine versus hexavalent pediatric vaccine that needs reconstitution?

Authors:  Andrew J Lloyd; Beenish Nafees; Eddy Ziani; Laurence Nicolas; Beth Alice Fordham; Benoit Soubeyrand; Christoph Bornhöft
Journal:  Patient Prefer Adherence       Date:  2015-10-27       Impact factor: 2.711

9.  A time motion study of community mental health workers in rural India.

Authors:  Vijaya Chebolu-Subramanian; Nachiket Sule; Richa Sharma; Nerges Mistry
Journal:  BMC Health Serv Res       Date:  2019-11-21       Impact factor: 2.655

10.  A phase III randomized, open-label, non-inferiority clinical trial comparing liquid and lyophilized formulations of oral live attenuated human rotavirus vaccine (HRV) in Indian infants.

Authors:  Catherine Cohet; Brigitte Cheuvart; Leentje Moerman; Dan Bi; Adrian Caplanusi; Mallesh Kariyappa; Sanjay Lalwani; Monjori Mitra; Amita Sapru; Shruti Saha; P V Varughese; Rajeev Zachariah Kompithra; Sanjay Gandhi
Journal:  Hum Vaccin Immunother       Date:  2021-08-24       Impact factor: 3.452
  10 in total

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