| Literature DB >> 19055349 |
Qiuping Ding1, Zhiyong Wang, Jie Wu.
Abstract
Tandem electrophilic cyclization-[3+2] cycloaddition-rearrangement reactions of 2-alkynylbenzaldoximes, DMAD, and bromine are described, which afford the unexpected isoquinoline-based azomethine ylides in good to excellent yields. The products could be further elaborated via palladium-catalyzed cross-coupling reactions to generate highly functionalized isoquinoline-based stable azomethine ylides.Entities:
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Year: 2009 PMID: 19055349 DOI: 10.1021/jo802076k
Source DB: PubMed Journal: J Org Chem ISSN: 0022-3263 Impact factor: 4.354