Literature DB >> 1905464

Chronic leg ulcers in sickle cell disease: experience in Ibadan, Nigeria.

M A Durosinmi1, S M Gevao, G J Esan.   

Abstract

The prevalence of chronic leg ulcers was investigated in 872 adults with sickle cell disease (SCD) (630 HbSS and 242 HbSC) at Ibadan, Nigeria. The incidence was 7.5% in HbSS and 1.7% in HbSC patients. The sex ratio in HbSS was 2:1 in favour of males, and three of the four HbSC were females. Ulcers were sited around the ankles in more than 70% of the patients. The duration of the ulcers varied from less than 1 year to more than 20 years. There was no bias for social class. Response to therapy, including autologous skin graft, was poor.

Entities:  

Mesh：

Year:  1991        PMID： 1905464

Source DB:  PubMed          Journal:  Afr J Med Med Sci        ISSN： 0309-3913


  8 in total

1.  Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway.

Authors:  Vikki G Nolan; Adeboye Adewoye; Clinton Baldwin; Ling Wang; Qianli Ma; Diego F Wyszynski; John J Farrell; Paola Sebastiani; Lindsay A Farrer; Martin H Steinberg
Journal:  Br J Haematol       Date:  2006-06       Impact factor: 6.998

Review 2.  Interventions for treating leg ulcers in people with sickle cell disease.

Authors:  Arturo J Martí-Carvajal; Jennifer M Knight-Madden; Maria José Martinez-Zapata
Journal:  Cochrane Database Syst Rev       Date:  2021-01-09

3.  Sickle Cell Disease in the Post Genomic Era: A Monogenic Disease with a Polygenic Phenotype.

Authors:  A Driss; K O Asare; J M Hibbert; B E Gee; T V Adamkiewicz; J K Stiles
Journal:  Genomics Insights       Date:  2009-07-30

4.  Lupus anticoagulant and leg ulcers in sickle cell anemia.

Authors:  Edeghonghon E Olayemi; Godwin N Bazuaye
Journal:  Indian J Dermatol       Date:  2009-07       Impact factor: 1.494

5.  A study of the geographic distribution and associated risk factors of leg ulcers within an international cohort of sickle cell disease patients: the CASiRe group analysis.

Authors:  Charles Antwi-Boasiako; Biree Andemariam; Raffaella Colombatti; Eugenia Vicky Asare; Crawford Strunk; Connie M Piccone; Deepa Manwani; Donna Boruchov; Fatimah Farooq; Rebekah Urbonya; Samuel Wilson; Gifty Dankwah Boatemaa; Silverio Perrotta; Laura Sainati; Angela Rivers; Sudha Rao; William Zempsky; Ivy Ekem; Fredericka Sey; Catherine Segbefia; Baba Inusa; Immacolata Tartaglione; Andrew D Campbell
Journal:  Ann Hematol       Date:  2020-05-06       Impact factor: 3.673

6.  Experiences with surgical treatment of chronic lower limb ulcers at a tertiary hospital in northwestern Tanzania: a prospective review of 300 cases.

Authors:  Fidelis Mbunda; Mabula D McHembe; Phillipo L Chalya; Peter Rambau; Stephen E Mshana; Benson R Kidenya; Japhet M Gilyoma
Journal:  BMC Dermatol       Date:  2012-09-28

Review 7.  Sickle cell disease: new opportunities and challenges in Africa.

Authors:  J Makani; S F Ofori-Acquah; O Nnodu; A Wonkam; K Ohene-Frempong
Journal:  ScientificWorldJournal       Date:  2013-09-19

Review 8.  Interventions for treating leg ulcers in people with sickle cell disease.

Authors:  Arturo J Martí-Carvajal; Jennifer M Knight-Madden; Maria José Martinez-Zapata
Journal:  Cochrane Database Syst Rev       Date:  2014-12-08
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.