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Literature DB >> 1905404

An oral treatment for lead toxicity.

Abstract

Chronic lead poisoning has traditionally been treated by parenteral agents. We present a case where a comparison of ethylene diaminetetra-acetic acid was made with 2,3-dimethyl succinic acid (DMSA) which has the advantage of oral administration associated with little toxicity and appeared to be at least as efficacious.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1991 PMID： 1905404 PMCID： PMC2398946 DOI： 10.1136/pgmj.67.783.63

Source DB: PubMed Journal: Postgrad Med J ISSN： 0032-5473 Impact factor: 2.401

14 in total

1. Meso-dimercaptosuccinic acid a chelating agent for the treatment of mercury and lead poisoning.

Authors: E Friedheim; C Crovi; C H Wakker
Journal: J Pharm Pharmacol Date: 1976-09 Impact factor: 3.765

2. Chelating therapy with Na-DMS in occupational lead and mercury intoxications.

Authors: S C Wang; K S Ting; C C Wu
Journal: Chin Med J Date: 1965-07

3. [Lead poisoning treated with 2,3-dimercaptosuccinic acid].

Authors: J F Devars du Mayne; C Prevost; B Gaudin; M Languille; M Cerf; Y Nordmann
Journal: Presse Med Date: 1984-10-13 Impact factor: 1.228

4. Meso-2,3-dimercaptosuccinic acid in the diagnosis and treatment of lead poisoning.

Authors: Y Bentur; J G Brook; R Behar; U Taitelman
Journal: J Toxicol Clin Toxicol Date: 1987

5. Dose-response study of oral 2,3-dimercaptosuccinic acid in children with elevated blood lead concentrations.

Authors: J H Graziano; N J Lolacono; P Meyer
Journal: J Pediatr Date: 1988-10 Impact factor: 4.406

Review 6. meso-2,3-Dimercaptosuccinic acid: chemical, pharmacological and toxicological properties of an orally effective metal chelating agent.

Authors: H V Aposhian; M M Aposhian
Journal: Annu Rev Pharmacol Toxicol Date: 1990 Impact factor: 13.820

7. Mobilization of lead by esters of meso-2,3-dimercaptosuccinic acid.

Authors: P K Singh; M M Jones; Z Xu; G R Gale; A B Smith; L M Atkins
Journal: J Toxicol Environ Health Date: 1989

8. Treatment of lead poisoning by 2,3-dimercaptosuccinic acid.

Authors: E Friedheim; J H Graziano; D Popovac; D Dragovic; B Kaul
Journal: Lancet Date: 1978-12-09 Impact factor: 79.321

9. Mobilization of lead over the course of DMSA chelation therapy and long-term efficacy.

Authors: D A Cory-Slechta
Journal: J Pharmacol Exp Ther Date: 1988-07 Impact factor: 4.030

10. Mobilization and redistribution of lead over the course of calcium disodium ethylenediamine tetraacetate chelation therapy.

Authors: D A Cory-Slechta; B Weiss; C Cox
Journal: J Pharmacol Exp Ther Date: 1987-12 Impact factor: 4.030

1 in total

1. An oral treatment for lead toxicity.

Authors: G W Ching; S M Rogers; R A Braithwaite; J A Vale
Journal: Postgrad Med J Date: 1991-10 Impact factor: 2.401

1 in total