Literature DB >> 19053722

A ratiometric fluorescent probe for cysteine and homocysteine displaying a large emission shift.

Weiying Lin1, Lingliang Long, Lin Yuan, Zengmei Cao, Bingbing Chen, Wen Tan.   

Abstract

4-(1H-phenanthro[9,10-d]imidazol-2-yl)benzaldehyde 1 was rationally designed as a novel ratiometric fluorescent probe for cysteine and homocysteine. Upon addition of cysteine or homocysteine, notably, the probe displayed a very large (125 nm) hypsochromic shift in emission due to switching off intramolecular charge transfer. This large emission wavelength shift may allow probe 1 to be employed for quantitatively detecting Cys/Hcy.

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Year:  2008        PMID： 19053722     DOI： 10.1021/ol802436j

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  14 in total

Review 1.  The concept of λ-ratiometry in fluorescence sensing and imaging.

Authors:  Alexander P Demchenko
Journal:  J Fluoresc       Date:  2010-04-01       Impact factor: 2.217

2.  2-(4-Formylphenyl)phenanthroimidazole as a colorimetric and fluorometric probe for selective fluoride ion sensing.

Authors:  Fanpeng Kong; Qingjian Liu; Xue Wu; Zhen Wang; Qing Chen; Lusheng Chen
Journal:  J Fluoresc       Date:  2011-02-24       Impact factor: 2.217

3.  Detection of biological thiols based on a colorimetric method.

Authors:  Yuan-Yuan Xu; Yang-Yang Sun; Yu-Juan Zhang; Chen-He Lu; Jin-Feng Miao
Journal:  J Zhejiang Univ Sci B       Date:  2016 Oct.       Impact factor: 3.066

4.  An ESIPT-Based Ratiometric Fluorescent Probe for Highly Sensitive and Rapid Detection of Sulfite in Living Cells.

Authors:  Yupeng Liu; Tian-Bing Ren; Dan Cheng; Jianing Hou; Dongdong Su; Lin Yuan
Journal:  ChemistryOpen       Date:  2019-10-07       Impact factor: 2.911

Review 5.  Molecular Probes, Chemosensors, and Nanosensors for Optical Detection of Biorelevant Molecules and Ions in Aqueous Media and Biofluids.

Authors:  Joana Krämer; Rui Kang; Laura M Grimm; Luisa De Cola; Pierre Picchetti; Frank Biedermann
Journal:  Chem Rev       Date:  2022-01-07       Impact factor: 60.622

6.  4-(4-Chloro-2-oxo-3(1H-phenanthro[9,10-d]imidazol-2-yl)-2H-chromen-6-yl) benzaldehyde as a fluorescent probe for medical imaging: linear and nonlinear optical properties.

Authors:  Przemystaw Krawczyk
Journal:  Photochem Photobiol Sci       Date:  2020-03-11       Impact factor: 3.982

7.  A Sensitive Ratiometric Long-Wavelength Fluorescent Probe for Selective Determination of Cysteine/Homocysteine.

Authors:  Kesavan Manibalan; Sin-Ming Chen; Veerappan Mani; Tsung-Tao Huang; Sheng-Tung Huang
Journal:  J Fluoresc       Date:  2016-06-11       Impact factor: 2.217

Review 8.  Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems.

Authors:  Vivian S Lin; Wei Chen; Ming Xian; Christopher J Chang
Journal:  Chem Soc Rev       Date:  2015-07-21       Impact factor: 54.564

9.  A dual-response BODIPY-based fluorescent probe for the discrimination of glutathione from cystein and homocystein.

Authors:  Feiyi Wang; Li Zhou; Chunchang Zhao; Rui Wang; Qiang Fei; Sihang Luo; Zhiqian Guo; He Tian; Wei-Hong Zhu
Journal:  Chem Sci       Date:  2015-02-18       Impact factor: 9.825

10.  A Two-Photon Fluorescent Probe for Lysosomal Thiols in Live Cells and Tissues.

Authors:  Jiangli Fan; Zhichao Han; Yao Kang; Xiaojun Peng
Journal:  Sci Rep       Date:  2016-01-22       Impact factor: 4.379
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