Literature DB >> 19052992

The hedgehog inhibitor cyclopamine induces apoptosis in leukemic cells in vitro.

Jörg Warzecha, Leonie Bonke, Ulrike Koehl, Doreen Munkelt, Stephan Göttig, Denis Percic, Mohammad Arabmotlagh, Andreas Kurth.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 19052992     DOI： 10.1080/10428190802510315

Source DB:  PubMed          Journal:  Leuk Lymphoma        ISSN： 1026-8022


× No keyword cloud information.
  7 in total

1.  Targeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemia.

Authors:  Xian Zeng; Hui Zhao; Yubin Li; Jiajun Fan; Yun Sun; Shaofei Wang; Ziyu Wang; Ping Song; Dianwen Ju
Journal:  Autophagy       Date:  2015       Impact factor: 16.016

2.  Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926.

Authors:  Tara L Lin; Qiuju H Wang; Patrick Brown; Craig Peacock; Akil A Merchant; Sarah Brennan; Evan Jones; Karen McGovern; D Neil Watkins; Kathleen M Sakamoto; William Matsui
Journal:  PLoS One       Date:  2010-12-28       Impact factor: 3.240

3.  Hedgehog pathway as a drug target: Smoothened inhibitors in development.

Authors:  Tara L Lin; William Matsui
Journal:  Onco Targets Ther       Date:  2012-03-09       Impact factor: 4.147

4.  GLI1 inhibitor GANT61 exhibits antitumor efficacy in T-cell lymphoma cells through down-regulation of p-STAT3 and SOCS3.

Authors:  Lingyun Geng; Kang Lu; Peipei Li; Xinyu Li; Xiangxiang Zhou; Ying Li; Xin Wang
Journal:  Oncotarget       Date:  2017-07-25

5.  MiR-520b promotes the progression of non-small cell lung cancer through activating Hedgehog pathway.

Authors:  Xiaoming Liu; Jichun Liu; Xuekang Zhang; Yuben Tong; Xin Gan
Journal:  J Cell Mol Med       Date:  2018-11-08       Impact factor: 5.310

6.  Profile of vismodegib and its potential in the treatment of advanced basal cell carcinoma.

Authors:  Muzafar A Macha; Surinder K Batra; Apar Kishor Ganti
Journal:  Cancer Manag Res       Date:  2013-07-31       Impact factor: 3.989

7.  Novel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia Cells.

Authors:  Alessandra Chiarenza; Fabrizio Manetti; Elena Petricci; Martial Ruat; Antonella Naldini; Maurizio Taddei; Fabio Carraro
Journal:  PLoS One       Date:  2016-03-02       Impact factor: 3.240
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.