Literature DB >> 19051658

Vaccination induced immunity to the hepatitis B virus among high-risk groups in Glasgow 1993-2001: evaluating the effectiveness of the United Kingdom's selective immunisation policy.

K M Roy1, D J Goldberg, K Wilson, S O Cameron.   

Abstract

BACKGROUND AND AIMS: The United Kingdom has adopted a selective approach to the control of hepatitis B (HBV), vaccinating those at increased risk of infection through lifestyle, occupation or other factors such as close contact with a case or carrier. This paper sought to assess the effectiveness of the targeted HBV vaccination programme, by determining the level of immunity and exposure to HBV infection among three high risk groups (injecting drug users (IDUs), men who have sex with men (MSM) and heterosexuals attending genitourinary medicine clinics) at three time points between 1993-2001 in Glasgow, Scotland.
METHODS: Residual sera from i) IDUs having a named HIV test and ii) MSM and heterosexual men and women attending GUM clinics and undergoing routine syphilis serology testing, were tested anonymously for HBV infection.
RESULTS: The overall prevalence of HBV infection remained at a low level in all three risk groups. IDUs continue to be the group at greatest risk of infection. DISCUSSION: Despite the implementation of new initiatives targeting high-risk groups, vaccination levels remain low in the populations studied.

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Year:  2008        PMID: 19051658     DOI: 10.1258/RSMSMJ.53.4.13

Source DB:  PubMed          Journal:  Scott Med J        ISSN: 0036-9330            Impact factor:   0.729


  5 in total

Review 1.  Hepatitis B/C in the countries of the EU/EEA: a systematic review of the prevalence among at-risk groups.

Authors:  Abby May Falla; Sanne Henrietta Ina Hofstraat; Erika Duffell; Susan Josien Maria Hahné; Lara Tavoschi; Irene Karen Veldhuijzen
Journal:  BMC Infect Dis       Date:  2018-02-12       Impact factor: 3.090

Review 2.  Bloodborne viral hepatitis infections among drug users: the role of vaccination.

Authors:  Fabio Lugoboni; Gianluca Quaglio; Paolo Civitelli; Paolo Mezzelani
Journal:  Int J Environ Res Public Health       Date:  2009-01-22       Impact factor: 3.390

3.  Selective hepatitis B virus vaccination has reduced hepatitis B virus transmission in the Netherlands.

Authors:  Susan Hahné; Robin van Houdt; Femke Koedijk; Marijn van Ballegooijen; Jeroen Cremer; Sylvia Bruisten; Roel Coutinho; Hein Boot
Journal:  PLoS One       Date:  2013-07-29       Impact factor: 3.240

Review 4.  Infection with hepatitis B and C virus in Europe: a systematic review of prevalence and cost-effectiveness of screening.

Authors:  Susan J M Hahné; Irene K Veldhuijzen; Lucas Wiessing; Tek-Ang Lim; Mika Salminen; Marita van de Laar
Journal:  BMC Infect Dis       Date:  2013-04-18       Impact factor: 3.090

5.  Prevalence of hepatitis B immunity and infection in home self-sampling HIV service users.

Authors:  Rachel Roche; Ruth Simmons; Louise Logan; Juan Ledesma; Caroline Sabin; Samreen Ijaz; Sema Mandal
Journal:  Sex Transm Infect       Date:  2021-06-30       Impact factor: 4.199

  5 in total

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