Literature DB >> 19049701

Therapeutic and predictive targets of AKI.

R Yalavarthy1, C L Edelstein.   

Abstract

Acute kidney injury (AKI) is a very common condition encountered in a hospital setting. AKI is an independent risk factor for in-hospital mortality. In this review, we discuss in detail about the tubular, inflammatory and vascular molecular targets of AKI which may result in therapies to improve mortality and biomarkers for earlier diagnosis of AKI.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 19049701      PMCID： PMC2872617          DOI： 10.5414/cnp70453

Source DB:  PubMed          Journal:  Clin Nephrol        ISSN： 0301-0430            Impact factor:   0.975


  82 in total

1.  Risk factors and outcome of hospital-acquired acute renal failure. Clinical epidemiologic study.

Authors:  N Shusterman; B L Strom; T G Murray; G Morrison; S L West; G Maislin
Journal:  Am J Med       Date:  1987-07       Impact factor: 4.965

2.  Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury.

Authors:  Jaya Mishra; Qing Ma; Anne Prada; Mark Mitsnefes; Kamyar Zahedi; Jun Yang; Jonathan Barasch; Prasad Devarajan
Journal:  J Am Soc Nephrol       Date:  2003-10       Impact factor: 10.121

3.  EPO and alpha-MSH prevent ischemia/reperfusion-induced down-regulation of AQPs and sodium transporters in rat kidney.

Authors:  Hong Gong; Weidong Wang; Tae-Hwan Kwon; Thomas Jonassen; Chunling Li; Troels Ring; Jørgen FrøkiAEr; Søren Nielsen
Journal:  Kidney Int       Date:  2004-08       Impact factor: 10.612

Review 4.  Inflammatory cells in ischemic acute renal failure.

Authors:  John J Friedewald; Hamid Rabb
Journal:  Kidney Int       Date:  2004-08       Impact factor: 10.612

5.  Erythropoietin protects against ischaemic acute renal injury.

Authors:  David A Vesey; Catherine Cheung; Betty Pat; Zoltan Endre; Glenda Gobé; David W Johnson
Journal:  Nephrol Dial Transplant       Date:  2004-02       Impact factor: 5.992

6.  The role of cell swelling in ischemic renal damage and the protective effect of hypertonic solute.

Authors:  J Flores; D R DiBona; C H Beck; A Leaf
Journal:  J Clin Invest       Date:  1972-01       Impact factor: 14.808

7.  Erythropoietin attenuates the tissue injury associated with hemorrhagic shock and myocardial ischemia.

Authors:  Maha Abdelrahman; Edward J Sharples; Michelle C McDonald; Marika Collin; Nimesh S A Patel; Muhammad M Yaqoob; Christoph Thiemermann
Journal:  Shock       Date:  2004-07       Impact factor: 3.454

8.  Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion.

Authors:  Edward J Sharples; Nimesh Patel; Paul Brown; Keith Stewart; Helder Mota-Philipe; Michael Sheaff; Julius Kieswich; David Allen; Steven Harwood; Martin Raftery; Christoph Thiemermann; Muhammad M Yaqoob
Journal:  J Am Soc Nephrol       Date:  2004-08       Impact factor: 10.121

9.  Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury.

Authors:  Takaharu Ichimura; Cheng Chieh Hung; Soon Ae Yang; James L Stevens; Joseph V Bonventre
Journal:  Am J Physiol Renal Physiol       Date:  2003-11-04

10.  Urinary interleukin-18 is a marker of human acute tubular necrosis.

Authors:  Chirag R Parikh; Alkesh Jani; Vyacheslav Y Melnikov; Sarah Faubel; Charles L Edelstein
Journal:  Am J Kidney Dis       Date:  2004-03       Impact factor: 8.860
View more
  6 in total

1.  Pulsed focused ultrasound pretreatment improves mesenchymal stromal cell efficacy in preventing and rescuing established acute kidney injury in mice.

Authors:  Scott R Burks; Ben A Nguyen; Pamela A Tebebi; Saejeong J Kim; Michele N Bresler; Ali Ziadloo; Jonathan M Street; Peter S T Yuen; Robert A Star; Joseph A Frank
Journal:  Stem Cells       Date:  2015-04       Impact factor: 6.277

Review 2.  Zebrafish kidney development: basic science to translational research.

Authors:  Lisa M Swanhart; Chiara Cianciolo Cosentino; Cuong Q Diep; Alan J Davidson; Mark de Caestecker; Neil A Hukriede
Journal:  Birth Defects Res C Embryo Today       Date:  2011-06

Review 3.  Mediators of inflammation in acute kidney injury.

Authors:  Ali Akcay; Quocan Nguyen; Charles L Edelstein
Journal:  Mediators Inflamm       Date:  2010-02-21       Impact factor: 4.711

Review 4.  Inflammation in AKI: Current Understanding, Key Questions, and Knowledge Gaps.

Authors:  Hamid Rabb; Matthew D Griffin; Dianne B McKay; Sundararaman Swaminathan; Peter Pickkers; Mitchell H Rosner; John A Kellum; Claudio Ronco
Journal:  J Am Soc Nephrol       Date:  2015-11-11       Impact factor: 10.121

5.  Systemic immune-inflammation index predicts postoperative acute kidney injury in hepatocellular carcinoma patients after hepatectomy.

Authors:  Jianjun Xu; Shaobo Hu; Suzhen Li; Weimin Wang; Yuzhe Wu; Zhe Su; Xing Zhou; Yang Gao; Xiang Cheng; Qichang Zheng
Journal:  Medicine (Baltimore)       Date:  2021-04-09       Impact factor: 1.817

Review 6.  The regulation of inflammatory mediators in acute kidney injury via exogenous mesenchymal stem cells.

Authors:  Tao Du; Ying-Jian Zhu
Journal:  Mediators Inflamm       Date:  2014-04-15       Impact factor: 4.711
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.