Literature DB >> 19049552

Informed shared decision making about immunotherapy for patients with multiple sclerosis (ISDIMS): a randomized controlled trial.

J Kasper1, S Köpke, I Mühlhauser, M Nübling, C Heesen.   

Abstract

BACKGROUND AND
PURPOSE: To evaluate the effects of an evidence-based patient decision aid (DA) on multiple sclerosis (MS) immunotherapy.
METHODS: Two hundred and ninety-seven MS patients who were considering or reconsidering immunotherapy participated in a randomized community-based controlled trial in Germany. An intervention group (IG) received the DA and a control group (CG) received standard information. Primary outcome measure was the match between the patient's preferred and actual roles during consultation with the physician. Secondary end-point was treatment choice. The course of the decision-making process and patients; evaluation of the decision were also evaluated. Data were collected at baseline, after receiving the information, after consultation with the physician and 6 months after baseline.
RESULTS: The percentage of preference matches did not differ between groups (IG 49%, CG 51%, P = 0.71). There were no differences in immunotherapy choices between groups. IG patients temporarily became more critical of immunotherapy and rated the information as significantly more helpful.
CONCLUSIONS: Although the intervention led to intensified processing of the information it affected neither the roles adopted in physician-patient encounters nor the immunotherapy choices made. Providing patients with balanced information may not be sufficient to alter the decision-making process.

Entities:  

Mesh:

Year:  2008        PMID: 19049552     DOI: 10.1111/j.1468-1331.2008.02313.x

Source DB:  PubMed          Journal:  Eur J Neurol        ISSN: 1351-5101            Impact factor:   6.089


  32 in total

Review 1.  Decision aids for patients.

Authors:  Matthias Lenz; Susanne Buhse; Jürgen Kasper; Ramona Kupfer; Tanja Richter; Ingrid Mühlhauser
Journal:  Dtsch Arztebl Int       Date:  2012-06-04       Impact factor: 5.594

Review 2.  Patients' perceptions of sharing in decisions: a systematic review of interventions to enhance shared decision making in routine clinical practice.

Authors:  France Légaré; Stéphane Turcotte; Dawn Stacey; Stéphane Ratté; Jennifer Kryworuchko; Ian D Graham
Journal:  Patient       Date:  2012       Impact factor: 3.883

3.  A Systematic Review of Discrete-Choice Experiments and Conjoint Analysis Studies in People with Multiple Sclerosis.

Authors:  Edward J D Webb; David Meads; Ieva Eskyte; Natalie King; Naila Dracup; Jeremy Chataway; Helen L Ford; Joachim Marti; Sue H Pavitt; Klaus Schmierer; Ana Manzano
Journal:  Patient       Date:  2018-08       Impact factor: 3.883

Review 4.  Patient-centered interventions to improve medication management and adherence: a qualitative review of research findings.

Authors:  Jennifer L Kuntz; Monika M Safford; Jasvinder A Singh; Shobha Phansalkar; Sarah P Slight; Qoua Liang Her; Nancy Allen Lapointe; Robin Mathews; Emily O'Brien; William B Brinkman; Kevin Hommel; Kevin C Farmer; Elissa Klinger; Nivethietha Maniam; Heather J Sobko; Stacy C Bailey; Insook Cho; Maureen H Rumptz; Meredith L Vandermeer; Mark C Hornbrook
Journal:  Patient Educ Couns       Date:  2014-09-16

Review 5.  Evaluating Treatment Decision for Multiple Sclerosis: Real Life and Patient Experiences.

Authors:  Hüsnü Efendi; Cavit Boz; Rana Karabudak
Journal:  Noro Psikiyatr Ars       Date:  2018       Impact factor: 1.339

Review 6.  Shared decision-making and comparative effectiveness research for patients with chronic conditions: an urgent synergy for better health.

Authors:  Michael R Gionfriddo; Aaron L Leppin; Juan P Brito; Annie Leblanc; Nilay D Shah; Victor M Montori
Journal:  J Comp Eff Res       Date:  2013-11       Impact factor: 1.744

7.  Impact of Shared Decision Making on Disease-Modifying Drug Adherence in Multiple Sclerosis.

Authors:  Aliza Ben-Zacharia; Meagan Adamson; Allison Boyd; Paula Hardeman; Jennifer Smrtka; Bryan Walker; Tracy Walker
Journal:  Int J MS Care       Date:  2018 Nov-Dec

8.  Shared Decision Making and Autonomy Among US Participants with Multiple Sclerosis in the NARCOMS Registry.

Authors:  Stacey S Cofield; Nina Thomas; Tuula Tyry; Robert J Fox; Amber Salter
Journal:  Int J MS Care       Date:  2017 Nov-Dec

9.  Identifying priority outcomes that influence selection of disease-modifying therapies in MS.

Authors:  Gregory S Day; Alexander Rae-Grant; Melissa J Armstrong; Tamara Pringsheim; Stacey S Cofield; Ruth Ann Marrie
Journal:  Neurol Clin Pract       Date:  2018-06

10.  Exploring Adherence to First-Line and Second-Line Immunotherapies in Multiple Sclerosis: An Interview Study.

Authors:  Gesa E A Pust; Benthe Untiedt; Jennifer Randerath; Anna Barabasch; Sascha Köpke; Anne C Rahn; Hilke Hansen; Christoph Heesen
Journal:  Int J MS Care       Date:  2020-01-22
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