M A Ndakotsu1, L Salawu, M A Durosinmi. 1. Department of Haematology and Blood Transfusion, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria. mndakotsu@yahoo.com
Abstract
BACKGROUND: The objective of this study was to determine the clinical and immunologic implications of an elevated ESR in HIV-infected patients. METHOD: One hundred and four consecutive HAART naïve human immunodeficiency virus (HIV)-infected adult patients and fifty one controls were studied. Detailed history was taken and full physical examination was conducted. Erythrocyte sedimentation rate (ESR), CD4+ T lymphocyte count, and complete blood count were performed. RESULTS: The mean (+/- SD) of ESR in the patients was 84.5 +/- 36.8 mm/1st one hour and that for the controls was 20.4 +/- 17.6 mm/1st one hour. The patients' ESR was significantly higher than those of the controls (p < 0.0001). There was a significant difference between the mean ESR of symptomatic (87.6 +/- 37.0 mm/1st hr) and asymptomatic patients (61.0 +/- 26.1 mm/1st hr) (p = 0.018), and between asymptomatic patients (mean +/- SD = 61 +/- 26.1 mm/1st one hour) and controls (mean +/- SD= 20.4 +/- 17.6 mm/1st one hour) (p = 0.000).The mean (+/- SD) CD4+ lymphocytes count of the patients and controls were 155.4 +/- 90.6 cells/microL, and 655.7 +/- 17.6 cells/microL, respectively. The CD4+ cells count was significantly lower in the patients than in the controls (p < 0.0001). CONCLUSION: ESR may be useful in monitoring HIV/AIDS disease.
BACKGROUND: The objective of this study was to determine the clinical and immunologic implications of an elevated ESR in HIV-infectedpatients. METHOD: One hundred and four consecutive HAART naïve human immunodeficiency virus (HIV)-infected adultpatients and fifty one controls were studied. Detailed history was taken and full physical examination was conducted. Erythrocyte sedimentation rate (ESR), CD4+ T lymphocyte count, and complete blood count were performed. RESULTS: The mean (+/- SD) of ESR in the patients was 84.5 +/- 36.8 mm/1st one hour and that for the controls was 20.4 +/- 17.6 mm/1st one hour. The patients' ESR was significantly higher than those of the controls (p < 0.0001). There was a significant difference between the mean ESR of symptomatic (87.6 +/- 37.0 mm/1st hr) and asymptomatic patients (61.0 +/- 26.1 mm/1st hr) (p = 0.018), and between asymptomatic patients (mean +/- SD = 61 +/- 26.1 mm/1st one hour) and controls (mean +/- SD= 20.4 +/- 17.6 mm/1st one hour) (p = 0.000).The mean (+/- SD) CD4+ lymphocytes count of the patients and controls were 155.4 +/- 90.6 cells/microL, and 655.7 +/- 17.6 cells/microL, respectively. The CD4+ cells count was significantly lower in the patients than in the controls (p < 0.0001). CONCLUSION: ESR may be useful in monitoring HIV/AIDS disease.
Authors: Joseph P Costello; Moses I Markowitz; Dylan Luxenburg; Michael G Rizzo; Rami H Mahmoud; Spencer W Barnhill; Fernando E Vilella-Hernandez Journal: J Orthop Date: 2022-08-10
Authors: Sourav Sen; Akshat Vyas; Sunil Sanghi; K Shanmuganandan; R M Gupta; Brig Ketoki Kapila; A K Praharaj; Satish Kumar; R B Batra Journal: Med J Armed Forces India Date: 2011-07-21