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Literature DB >> 1904750

A dose-response study examining the effects of ritanserin on human slow wave sleep.

Abstract

This study investigated the effects of placebo, 1 mg, 3 mg, 10 mg and 30 mg ritanserin and 10 mg diazepam on human sleep. Twelve normal volunteers participated in this randomized, double-blind, placebo-controlled cross-over sleep study. A clear dose-response relationship was found for ritanserin with higher doses evoking increased duration of slow wave sleep.

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Year: 1991 PMID： 1904750 PMCID： PMC1368392 DOI： 10.1111/j.1365-2125.1991.tb05514.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

6 in total

1. 5-Hydroxytryptamine-2 antagonist increases human slow wave sleep.

Authors: C Idzikowski; F J Mills; R Glennard
Journal: Brain Res Date: 1986-07-16 Impact factor: 3.252

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Authors: C Idzikowski; P J Cowen; D Nutt; F J Mills
Journal: Psychopharmacology (Berl) Date: 1987 Impact factor: 4.530

3. Effects of repeated ritanserin on middle-aged poor sleepers.

Authors: K Adam; I Oswald
Journal: Psychopharmacology (Berl) Date: 1989 Impact factor: 4.530

4. Suppression of sleep-related prolactin secretion and enhancement of sleep-related growth hormone secretion.

Authors: W B Mendelson; L S Jacobs; J D Reichman; E Othmer; P E Cryer; B Trivedi; W H Daughaday
Journal: J Clin Invest Date: 1975-09 Impact factor: 14.808

5. Trazodone enhances sleep in subjective quality but not in objective duration.

Authors: I Montgomery; I Oswald; K Morgan; K Adam
Journal: Br J Clin Pharmacol Date: 1983-08 Impact factor: 4.335

6. Effects of ritanserin on sleep disturbances of dysthymic patients.

Authors: T Paiva; F Arriaga; A Wauquier; E Lara; R Largo; J N Leitao
Journal: Psychopharmacology (Berl) Date: 1988 Impact factor: 4.530

6 in total

13 in total

1. 5-HT2 receptors are partially involved in the relationship between renin release and delta relative power.

Authors: G Brandenberger; R Luthringer; G Muller; C Gronfier; N Schaltenbrand; J P Macher; A Muzet; M Follenius
Journal: J Endocrinol Invest Date: 1996-09 Impact factor: 4.256

2. The effects of a 5-HT2 receptor antagonist (ICI 169,369) on changes in waking EEG, pupillary responses and state of arousal in human volunteers.

Authors: D S Millson; S J Haworth; A Rushton; D Wilkinson; S Hobson; J Harry
Journal: Br J Clin Pharmacol Date: 1991-10 Impact factor: 4.335

3. Drug-related Sleep Stage Changes: Functional Significance and Clinical Relevance.

Authors: Timothy Roehrs; Thomas Roth
Journal: Sleep Med Clin Date: 2010-12-01

4. NREM sleep stage transitions control ultradian REM sleep rhythm.

Authors: Akifumi Kishi; Hideaki Yasuda; Takahisa Matsumoto; Yasushi Inami; Jun Horiguchi; Masako Tamaki; Zbigniew R Struzik; Yoshiharu Yamamoto
Journal: Sleep Date: 2011-10-01 Impact factor: 5.849

5. Pimavanserin tartrate, a 5-HT(2A) receptor inverse agonist, increases slow wave sleep as measured by polysomnography in healthy adult volunteers.

Authors: Sonia Ancoli-Israel; Kimberly E Vanover; David M Weiner; Robert E Davis; Daniel P van Kammen
Journal: Sleep Med Date: 2011-01-21 Impact factor: 3.492

9. Increased wakefulness, motor activity and decreased theta activity after blockade of the 5-HT2B receptor by the subtype-selective antagonist SB-215505.

Authors: Sandor Kantor; Rita Jakus; Brigitta Balogh; Anita Benko; Gyorgy Bagdy
Journal: Br J Pharmacol Date: 2004-07-20 Impact factor: 8.739

Review 10. Human slow wave sleep: a review and appraisal of recent findings, with implications for sleep functions, and psychiatric illness.

Authors: J Horne
Journal: Experientia Date: 1992-10-15