Literature DB >> 19046753

Cervical tumor caused by the sexually mature stage of Fasciola hepatica.

Luis A Marcos1, Pedro Légua, Juvenal Sánchez, José R Espinoza, Pedro Yi, Manuel Tantaleán.   

Abstract

A 58-year-old man presented with an asymptomatic 5cm left anterior cervical tumor that had been present for over a year. Histological analysis revealed chronic inflammation and granuloma with giant cells surrounding Fasciola hepatica eggs. Fas2 antigen was detected in the tissue by immunohistochemistry. Serology for F. hepatica was positive, but stool examinations were negative and eosinophil count was normal. A month later, the tumor recurred, and an adult parasite was found during excision. The patient received triclabendazole, and after 6 months serology was negative. Erratic localization of F. hepatica reveals a pathology involving chronic inflammation caused by a sexually mature parasite, although according to theory only immature parasites are located in ectopic lesions.

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Year:  2008        PMID: 19046753     DOI: 10.1016/j.trstmh.2008.10.024

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


  2 in total

1.  Extra-hepatic fascioliasis with peritoneal malignancy tumor feature.

Authors:  Behnam Mohammadi-Ghalehbin; Mir Mehdi Chinifroush-Asl; Fatemeh Ramzi
Journal:  J Parasit Dis       Date:  2011-12-08

2.  Triclabendazole in the treatment of human fascioliasis: a review.

Authors:  Preetam Gandhi; Esther K Schmitt; Chien-Wei Chen; Sanjay Samantray; Vinay Kumar Venishetty; David Hughes
Journal:  Trans R Soc Trop Med Hyg       Date:  2019-12-01       Impact factor: 2.184

  2 in total

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