Literature DB >> 19046173

Panton-Valentine leukocidin is expressed at toxic levels in human skin abscesses.

C Badiou1, O Dumitrescu, M Croze, Y Gillet, B Dohin, D H Slayman, B Allaouchiche, J Etienne, F Vandenesch, G Lina.   

Abstract

Pus samples were prospectively collected from patients with Staphylococcus aureus skin infections and tested for Panton-Valentine leukocidin (PVL). PVL was detected at concentrations that were toxic for rabbit skin in all specimens from patients infected with strains harbouring PVL genes.

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Year:  2008        PMID： 19046173     DOI： 10.1111/j.1469-0691.2008.02105.x

Source DB:  PubMed          Journal:  Clin Microbiol Infect        ISSN： 1198-743X            Impact factor:   8.067


  25 in total

1.  Do differences in Panton-Valentine leukocidin production among international methicillin-resistant Staphylococcus aureus clones affect disease presentation and severity?

Authors:  Eve Boakes; Angela M Kearns; Cederic Badiou; Gerard Lina; Robert L Hill; Matthew J Ellington
Journal:  J Clin Microbiol       Date:  2012-01-11       Impact factor: 5.948

Review 2.  Virulence strategies of the dominant USA300 lineage of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA).

Authors:  Lance R Thurlow; Gauri S Joshi; Anthony R Richardson
Journal:  FEMS Immunol Med Microbiol       Date:  2012-03-05

3.  Relative contribution of Panton-Valentine leukocidin to PMN plasma membrane permeability and lysis caused by USA300 and USA400 culture supernatants.

Authors:  Shawna F Graves; Scott D Kobayashi; Kevin R Braughton; Binh An Diep; Henry F Chambers; Michael Otto; Frank R Deleo
Journal:  Microbes Infect       Date:  2010-02-19       Impact factor: 2.700

Review 4.  The potential use of toxin antibodies as a strategy for controlling acute Staphylococcus aureus infections.

Authors:  Gordon Y C Cheung; Michael Otto
Journal:  Expert Opin Ther Targets       Date:  2012-04-25       Impact factor: 6.902

5.  Sublytic concentrations of Staphylococcus aureus Panton-Valentine leukocidin alter human PMN gene expression and enhance bactericidal capacity.

Authors:  Shawna F Graves; Scott D Kobayashi; Kevin R Braughton; Adeline R Whitney; Daniel E Sturdevant; Devon L Rasmussen; Liliya N Kirpotina; Mark T Quinn; Frank R DeLeo
Journal:  J Leukoc Biol       Date:  2012-05-11       Impact factor: 4.962

Review 6.  Role of pore-forming toxins in bacterial infectious diseases.

Authors:  Ferdinand C O Los; Tara M Randis; Raffi V Aroian; Adam J Ratner
Journal:  Microbiol Mol Biol Rev       Date:  2013-06       Impact factor: 11.056

7.  Prompt and successful toxin-targeting treatment of three patients with necrotizing pneumonia due to Staphylococcus aureus strains carrying the Panton-Valentine leukocidin genes.

Authors:  Nicolas Rouzic; Frédéric Janvier; Nicolas Libert; Etienne Javouhey; Gerard Lina; Jacques-Yves Nizou; Pierre Pasquier; Didier Stamm; Louis Brinquin; Christophe Pelletier; François Vandenesch; Daniel Floret; Jerome Etienne; Yves Gillet
Journal:  J Clin Microbiol       Date:  2010-02-03       Impact factor: 5.948

8.  Staphylococcus aureus leukotoxin GH promotes formation of neutrophil extracellular traps.

Authors:  Natalia Malachowa; Scott D Kobayashi; Brett Freedman; David W Dorward; Frank R DeLeo
Journal:  J Immunol       Date:  2013-11-04       Impact factor: 5.422

9.  Panton-valentine leukocidin enhances the severity of community-associated methicillin-resistant Staphylococcus aureus rabbit osteomyelitis.

Authors:  Anne-Claude Crémieux; Oana Dumitrescu; Gerard Lina; Christian Vallee; Jean-François Côté; Martine Muffat-Joly; Thomas Lilin; Jerome Etienne; François Vandenesch; Azzam Saleh-Mghir
Journal:  PLoS One       Date:  2009-09-25       Impact factor: 3.240

10.  Staphylococcus aureus Panton-Valentine leukocidin contributes to inflammation and muscle tissue injury.

Authors:  Ching Wen Tseng; Pierre Kyme; Jennifer Low; Miguel A Rocha; Randa Alsabeh; Loren G Miller; Michael Otto; Moshe Arditi; Binh An Diep; Victor Nizet; Terence M Doherty; David O Beenhouwer; George Y Liu
Journal:  PLoS One       Date:  2009-07-27       Impact factor: 3.240
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