Literature DB >> 19045537

Analysis of flow disturbance in a stenosed carotid artery bifurcation using two-equation transitional and turbulence models.

F P P Tan1, G Soloperto, S Bashford, N B Wood, S Thom, A Hughes, X Y Xu.   

Abstract

In this study, newly developed two-equation turbulence models and transitional variants are employed for the prediction of blood flow patterns in a diseased carotid artery where the growth, progression, and structure of the plaque at rupture are closely linked to low and oscillating wall shear stresses. Moreover, the laminar-turbulent transition in the poststenotic zone can alter the separation zone length, wall shear stress, and pressure distribution over the plaque, with potential implications for stresses within the plaque. Following the validation with well established experimental measurements and numerical studies, a magnetic-resonance (MR) image-based model of the carotid bifurcation with 70% stenosis was reconstructed and simulated using realistic patient-specific conditions. Laminar flow, a correlation-based transitional version of Menter's hybrid k-epsilon/k-omega shear stress transport (SST) model and its "scale adaptive simulation" (SAS) variant were implemented in pulsatile simulations from which analyses of velocity profiles, wall shear stress, and turbulence intensity were conducted. In general, the transitional version of SST and its SAS variant are shown to give a better overall agreement than their standard counterparts with experimental data for pulsatile flow in an axisymmetric stenosed tube. For the patient-specific case reported, the wall shear stress analysis showed discernable differences between the laminar flow and SST transitional models but virtually no difference between the SST transitional model and its SAS variant.

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Year:  2008        PMID: 19045537     DOI: 10.1115/1.2978992

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN: 0148-0731            Impact factor:   2.097


  7 in total

Review 1.  Current progress in patient-specific modeling.

Authors:  Maxwell Lewis Neal; Roy Kerckhoffs
Journal:  Brief Bioinform       Date:  2009-12-02       Impact factor: 11.622

2.  Numerical analysis of the effect of turbulence transition on the hemodynamic parameters in human coronary arteries.

Authors:  Arun Mahalingam; Udhav Ulhas Gawandalkar; Girish Kini; Abdulrajak Buradi; Tadashi Araki; Nobutaka Ikeda; Andrew Nicolaides; John R Laird; Luca Saba; Jasjit S Suri
Journal:  Cardiovasc Diagn Ther       Date:  2016-06

3.  Pulse Wave Imaging in Carotid Artery Stenosis Human Patients in Vivo.

Authors:  Ronny X Li; Iason Z Apostolakis; Paul Kemper; Matthew D J McGarry; Ada Ip; Edward S Connolly; James F McKinsey; Elisa E Konofagou
Journal:  Ultrasound Med Biol       Date:  2018-11-12       Impact factor: 2.998

4.  Geometric determinants of local hemodynamics in severe carotid artery stenosis.

Authors:  Dara Azar; William M Torres; Lindsey A Davis; Taylor Shaw; John F Eberth; Vijaya B Kolachalama; Susan M Lessner; Tarek Shazly
Journal:  Comput Biol Med       Date:  2019-09-05       Impact factor: 4.589

5.  Assessment of Influences of Stenoses in Right Carotid Artery on Left Carotid Artery Using Wall Stress Marker.

Authors:  Arindam Bit; Dushali Ghagare; Albert A Rizvanov; Himadri Chattopadhyay
Journal:  Biomed Res Int       Date:  2017-01-15       Impact factor: 3.411

6.  The study on hemodynamic effect of series type LVAD on aortic blood flow pattern: a primary numerical study.

Authors:  Qi Zhang; Bin Gao; Yu Chang
Journal:  Biomed Eng Online       Date:  2016-12-28       Impact factor: 2.819

7.  Haemodynamic Analysis of Branched Endografts for Complex Aortic Arch Repair.

Authors:  Sampad Sengupta; Mohamad Hamady; Xiao-Yun Xu
Journal:  Bioengineering (Basel)       Date:  2022-01-18
  7 in total

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