Literature DB >> 1904383

Cloning and characterization of a DNA fragment that complements the nfxB mutation in Pseudomonas aeruginosa PAO.

T Okazaki1, S Iyobe, H Hashimoto, K Hirai.   

Abstract

The 2.2-kilobase DNA fragment that can complement the nfxB mutation in Pseudomonas aeruginosa PAO was cloned from chromosomal DNA of P. aeruginosa PAO1. The nfxB mutants show an increase in resistance to quinolones and hypersusceptibility to beta-lactam and aminoglycoside antibiotics. In the mutants, a 54 kDa outer membrane protein newly appeared. The phenotype was restored to the wild-type by transformation with plasmid carrying the 2.2-kb DNA fragment.

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Year:  1991        PMID： 1904383     DOI： 10.1016/0378-1097(91)90522-c

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN： 0378-1097            Impact factor:   2.742


  11 in total

Review 1.  Efflux-mediated resistance to fluoroquinolones in gram-negative bacteria.

Authors:  K Poole
Journal:  Antimicrob Agents Chemother       Date:  2000-09       Impact factor: 5.191

2.  Triclosan can select for an AdeIJK-overexpressing mutant of Acinetobacter baumannii ATCC 17978 that displays reduced susceptibility to multiple antibiotics.

Authors:  Dinesh M Fernando; Wayne Xu; Peter C Loewen; George G Zhanel; Ayush Kumar
Journal:  Antimicrob Agents Chemother       Date:  2014-08-18       Impact factor: 5.191

3.  Purification and characterization of the Pseudomonas aeruginosa NfxB protein, the negative regulator of the nfxB gene.

Authors:  T Shiba; K Ishiguro; N Takemoto; H Koibuchi; K Sugimoto
Journal:  J Bacteriol       Date:  1995-10       Impact factor: 3.490

4.  Quantitative correlation between susceptibility and OprJ production in NfxB mutants of Pseudomonas aeruginosa.

Authors:  N Masuda; N Gotoh; S Ohya; T Nishino
Journal:  Antimicrob Agents Chemother       Date:  1996-04       Impact factor: 5.191

5.  Mechanisms of high-level resistance to quinolones in urinary tract isolates of Pseudomonas aeruginosa.

Authors:  T Yoshida; T Muratani; S Iyobe; S Mitsuhashi
Journal:  Antimicrob Agents Chemother       Date:  1994-07       Impact factor: 5.191

6.  Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump.

Authors:  Katy Jeannot; Sylvie Elsen; Thilo Köhler; Ina Attree; Christian van Delden; Patrick Plésiat
Journal:  Antimicrob Agents Chemother       Date:  2008-05-12       Impact factor: 5.191

7.  Cloning and nucleotide sequence of Pseudomonas aeruginosa DNA gyrase gyrA gene from strain PAO1 and quinolone-resistant clinical isolates.

Authors:  A Kureishi; J M Diver; B Beckthold; T Schollaardt; L E Bryan
Journal:  Antimicrob Agents Chemother       Date:  1994-09       Impact factor: 5.191

8.  Occurrence of the nfxB type mutation in clinical isolates of Pseudomonas aeruginosa.

Authors:  E B Jakics; S Iyobe; K Hirai; H Fukuda; H Hashimoto
Journal:  Antimicrob Agents Chemother       Date:  1992-11       Impact factor: 5.191

9.  Purification of a 54-kilodalton protein (OprJ) produced in NfxB mutants of Pseudomonas aeruginosa and production of a monoclonal antibody specific to OprJ.

Authors:  M Hosaka; N Gotoh; T Nishino
Journal:  Antimicrob Agents Chemother       Date:  1995-08       Impact factor: 5.191

10.  nfxB as a novel target for analysis of mutation spectra in Pseudomonas aeruginosa.

Authors:  Mariela R Monti; Natalia R Morero; Virginia Miguel; Carlos E Argaraña
Journal:  PLoS One       Date:  2013-06-07       Impact factor: 3.240
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