Literature DB >> 1904356

Inhibition of cholesterol absorption by HMG-CoA reductase inhibitor.

T A Miettinen1.   

Abstract

In subjects with familial hypercholesterolemia cholesterol absorption efficiency was insignificantly reduced during a short-term more consistently during long-term pravastatin treatment. A cholesterol feeding had no effect on LDL cholesterol level but reduced absorption efficiency during a long-term lovastatin treatment.

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Year:  1991        PMID： 1904356

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  17 in total

1.  Serum cholestanol and plant sterol levels in relation to cholesterol metabolism in middle-aged men.

Authors:  T A Miettinen; R S Tilvis; Y A Kesäniemi
Journal:  Metabolism       Date:  1989-02       Impact factor: 8.694

Review 2.  HMG-CoA reductase inhibitors for treatment of hypercholesterolemia.

Authors:  S M Grundy
Journal:  N Engl J Med       Date:  1988-07-07       Impact factor: 91.245

3.  Substrate specificity of lecithin:cholesterol acyltransferase. Esterification of desmosterol, b-sitosterol, and cholecalciferol in human plasma.

Authors:  G Nordby; K R Norum
Journal:  Scand J Clin Lab Invest       Date:  1975-11       Impact factor: 1.713

4.  Cholesterol metabolism during ketoconazole treatment in man.

Authors:  T A Miettinen
Journal:  J Lipid Res       Date:  1988-01       Impact factor: 5.922

5.  Inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase by mevinolin in familial hypercholesterolemia heterozygotes: effects on cholesterol balance.

Authors:  S M Grundy; D W Bilheimer
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

6.  Reduction in plasma low-density lipoprotein cholesterol and urinary mevalonic acid by lovastatin in patients with heterozygous familial hypercholesterolemia.

Authors:  A S Pappu; D R Illingworth; S Bacon
Journal:  Metabolism       Date:  1989-06       Impact factor: 8.694

7.  Serum plant sterols and their relation to cholesterol absorption.

Authors:  R S Tilvis; T A Miettinen
Journal:  Am J Clin Nutr       Date:  1986-01       Impact factor: 7.045

8.  Cholesterol absorption: regulation of cholesterol synthesis and elimination and within-population variations of serum cholesterol levels.

Authors:  T A Miettinen; Y A Kesäniemi
Journal:  Am J Clin Nutr       Date:  1989-04       Impact factor: 7.045

9.  Effects of MK-733 (simvastatin), an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on intestinal acylcoenzyme A:cholesterol acyltransferase activity in rabbits.

Authors:  F Ishida; A Sato; Y Iizuka; K Kitani; Y Sawasaki; T Kamei
Journal:  Biochim Biophys Acta       Date:  1989-07-17

10.  A lack of esterification of lanosterol and other methyl sterols in human serum in vitro.

Authors:  R S Tilvis; T A Miettinen
Journal:  Scand J Clin Lab Invest       Date:  1980       Impact factor: 1.713
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  3 in total

1.  Treatment of patients with familial defective apolipoprotein B-100 with pravastatin and gemfibrozil: a two-period cross-over study.

Authors:  P S Hansen; H Meinertz; L U Gerdes; I C Klausen; O Faergeman
Journal:  Clin Investig       Date:  1994-12

2.  Effects of lovastatin and dietary cholesterol on sterol homeostasis in healthy human subjects.

Authors:  W C Duane
Journal:  J Clin Invest       Date:  1993-08       Impact factor: 14.808

3.  Cholesterol malabsorption caused by sitostanol ester feeding and neomycin in pravastatin-treated hypercholesterolaemic patients.

Authors:  H Vanhanen
Journal:  Eur J Clin Pharmacol       Date:  1994       Impact factor: 2.953
  3 in total

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